CAS 22059-60-5 MFCD00069254-4-(Diisopropylamino)-2-Phenyl-2-(Pyridin-2-Yl)Butanamide Phosphate 4-(二异丙氨基)-2-苯基-2-(吡啶-2-基)丁酰胺磷酸盐 TAO{mole}

4-(Diisopropylamino)-2-Phenyl-2-(Pyridin-2-Yl)Butanamide Phosphate 4-(二异丙氨基)-2-苯基-2-(吡啶-2-基)丁酰胺磷酸盐

CAS 22059-60-5 MFCD00069254

化学结构图

SMILES: CC(C)N(CCC(C(N)=O)(C1C=CC=CN=1)C1C=CC=CC=1)C(C)C.OP(O)(O)=O

化学属性

Mol. Formula	C21H29N3O · H3PO4
Mol. Weight	437.47

别名和识别编码

Chemical Name	4-(Diisopropylamino)-2-Phenyl-2-(Pyridin-2-Yl)Butanamide Phosphate
Synonym	2-[1-(ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)]pyridinium phosphate; Norpace CR 双异丙吡胺 alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide 达舒平磷酸盐
MDL Number	MFCD00069254
PubChem Substance ID	24277706
EC Number	244-756-1
CAS Number	22059-60-5
Chemical Name Translation	4-(二异丙氨基)-2-苯基-2-(吡啶-2-基)丁酰胺磷酸盐
Wiswesser Line Notation	T6NJ BYVZR B2N3&3 &..H3.P-O4

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

WGK Germany3

GHS Symbol

Signal word Warning

Hazard statements

H302 Harmful if swallowed 吞食有害

RTECSUR8440000

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；

Hazard Codes Xn

Risk Statements

R22 Harmful if swallowed 吞咽有害

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 214 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JATOD3 Journal of Analytical Toxicology.  (Preston Pub. Inc., POB 48312,
   Niles, IL 60648) V.1-    1977-  Volume(issue)/page/year: 6,255,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 43 mg/kg/5D-I
TOXIC EFFECTS :
   Endocrine - hypoglycemia
REFERENCE :
   NYSJAM New York State Journal of Medicine.  (Medical Soc. of the State of
   New York, POB 5405, Lake Success, NY 11042)  V.1-    1901-
   Volume(issue

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - pulse rate increase, without fall in BP
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   JZKEDZ Jitchuken Zenrinsho Kenkyuho.  Central Institute for Experimental
   Animals, Research Reports. (Jikken Dobutsu Chuo Kenkyusho, 1433 Nogawa,
   Takatsu-ku, Kawasaki 211, Japan)  V.1-    1975-  Volume(issue)/page/year:
   6,147,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 255 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Ja

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2240 mg/kg
SEX/DURATION            : female 17-22 day(s) after conception
                          lactating female 26 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   JZKEDZ Jitchuken Zenrinsho Kenkyuho.  Central Institute for Experimental
   Animals, Research Reports. (Jikken Dobutsu Chuo Kenkyusho, 1433 Nogawa,
   Takatsu-ku, Kawasaki 211, Japan)  V.1-    1975-  Volume(issue)/page/year:
   10,111,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 770 mg/kg
SEX/DURATION            : female 7-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   JZKEDZ Jitchuken Zenrinsho Kenkyuho.  Central Institute for Experimental
   Animals, Research Reports. (Jikken Dobutsu Chuo Kenkyusho, 1433 Nogawa,
   Takatsu-ku, Kawasaki 211, Ja

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4095 mg/kg
SEX/DURATION            : male 10 week(s) pre-mating
                          female 2 week(s) pre-mating  - 7 day(s) after
                          conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JZKEDZ Jitchuken Zenrinsho Kenkyuho.  Central Institute for Experimental
   Animals, Research Reports. (Jikken Dobutsu Chuo Kenkyusho, 1433 Nogawa,
   Takatsu-ku, Kawasaki 211, Japan)  V.1-    1975-  Volume(issue)/page/year:
   7,145,1981