25-Hydroxycholesterol 25-羟基胆甾醇
CAS 2140-46-7 MFCD00057815
化学结构图
SMILES: C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@@]21C
化学属性
| Mol. Formula | C27H46O2 |
|---|---|
| Mol. Weight | 403 |
别名和识别编码
| Chemical Name | 25-Hydroxycholesterol |
|---|---|
| CAS Number | 2140-46-7 |
| Synonym | Cholest-5-ene-3?,25-diol 5-Cholesten-3?,25-diol 25-Hydroxy-5-cholestene-3?-ol (3?)-Cholest-5-ene-3,25-diol 25-羟基胆固醇 25-羟基胆甾醇 5-胆甾烯-3β,25-二醇 |
| MDL Number | MFCD00057815 |
| Beilstein Registry Number | 3161259 |
| Chemical Name Translation | 25-羟基胆甾醇 |
| PubChem Substance ID | 65094 |
| InChI | InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 |
| LabNetwork Molecule ID | LN01289776 |
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分类
- {SNA} Anti-Proliferative Agents, Antitumor Agents, Bile Acid Metabolism, Biochemicals and Reagents, Cell Biology,
- {S
- {SNA} Anti-Proliferative Agents, Cholesterol and Derivatives, Sterol Lipids, 代谢组学, 代谢通路, 抗肿瘤药物, 生化试剂, 癌症研究, 细胞生物学, 胆汁酸代谢, 脂类
- Inhibitors
- {SNA} Anti-Proliferative Agents, Antitumor Agents, Bile Acid Metabolism, Biochemicals and Reagents, Cholesterol and Derivatives, Lipids, Metabolic Pathways, Sterol Lipids, 代谢组学, 癌症研究, 细胞生物学
- Steroids
- Pharmaceuticals
- {SNA} Anti-Prol
产品应用
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相关文献及参考
- Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);
- [1]. McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88(6):1071-2.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H332 Harmful if inhaled 吸入有害
- H315 Causes skin irritation 会刺激皮肤
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H319 Causes serious eye irritation 严重刺激眼睛
- H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R48 Danger of serious damage to health by prolonged exposure 长期接触有严重损害健康的危险
