CAS 2068-78-2 MFCD00084729-Vincristine Sulfate 硫酸长春新碱 TAO{mole}

Vincristine Sulfate 硫酸长春新碱

CAS 2068-78-2 MFCD00084729

化学结构图

SMILES: CC(=O)O[C@@H]1[C@]2(CC)C=CCN3CC[C@]4([C@@H](N(C=O)C5C=C(OC)C(=CC4=5)[C@]4(C[C@@H]5C[C@](O)(CN(C5)CCC5=C4NC4C=CC=CC5=4)CC)C(=O)OC)[C@@]1(O)C(=O)OC)[C@H]23.OS(O)(=O)=O |&1:4,5,14,15,27,29,31,53,59|

化学属性

Mol. Formula	C46H58N4O14S
Mol. Weight	923
Melting Point	300
Solubility	>=1 G/100 ML AT 24 ºC
TSCA	No
Boiling Point	273-281°
Appearance	lyophilized powder

别名和识别编码

Chemical Name	Vincristine Sulfate
MDL Number	MFCD00084729
CAS Number	2068-78-2
Synonym	lilly37231 22-OXOVINCALEUKOBLASTINE SULFATE SALT 长春新碱硫酸醛基长春碱 VCR 醛基长春碱硫酸盐长春醛碱硫酸盐硫酸长春新碱 LEUROCRISTINE SULFATE VINCRISTINE SULFATE VCR 醛基长春碱硫酸盐长春新碱硫酸盐长春醛碱硫酸盐 leurocristinesulfate(1:1) 长春新碱硫化物硫酸醛基长春碱,硫酸长春醛碱长春新碱硫酸盐 22-OXOVINCALEUKO-BLASTINE SULFATE VINCRISTINE SULFATE, APOCYNACEAE SPECIES 22-OXOVINCALEUKOBLASTINE 长春地辛 LEUROCRISTINE 硫酸长春醛碱长春新碱硫酸酯 VCR kyocristine 22-oxo-vincaleukoblastinsulfate(1:1)(salt) VINCRISTINE SULFATE SAL oncovin
Beilstein Registry Number	3924631
EC Number	218-190-0
PubChem Substance ID	24900771
Merck Number	14,9986
Chemical Name Translation	硫酸长春新碱

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分类

{SNA} Antibacterial, Antibiotics A to Z, Antibiotics T-Z, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Core Bioreagents, Enzyme Inhibitors, L - Z, Pharmacopoeia, Pharmacopoeia A-Z, Pharmacopoeial Antibiotics, Research Essentials, Spectrum of Activity, 分析/色谱, 抗生素, 生化试剂
{SNA} Analytical Standards,
{SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, Apoptosis and Cell Cycle, Application Index, Biochemicals and Rea

产品应用

广泛地用于癌症研究，多药物抑制，单胺氧化酶（monoamine oxidase）抑制剂。

安全信息

WGK Germany3

RTECSOH6340000

Hazard Codes T

Safety Statements

S22 Do not breathe dust 不要吸入粉尘；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
R25 Toxic if swallowed 吞咽有毒
R62 Possible risk of impaired fertility 有削弱生殖能力的危险
R63 Possible risk of harm to the unborn child 可能危害未出生婴儿

UN Number UN 2811 6.1/PG 2

GHS Symbol

Hazard statements

H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
H300 Fatal if swallowed 吞食致命

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P301+P310
P281 Use personal protective equipment as required. 使用所需的个人防护装备。

Signal word

Packing GroupII

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Storage condition 2-8°C 存储温度-20℃

其他信息

MOL 文件:2068-78-2.mol
HazardClass:6.1(a)
PackingGroup:II
RTECS号:OH6340000
硫酸长春新碱价格(试剂级):更新日期产品编号产品名称包装价格 2010/06/21 203440050 硫酸长春新碱 Vincristine sulfate 95% 5 MG 2007元
水溶性:＞=1 g/100 mL at 24℃
F:8-10
用途:天然植物抗肿瘤药，用于治疗急性白血病和恶性淋巴瘤，小细胞肺癌及乳腺癌。
EPA化学物质信息:Vincaleukoblastine, 22-oxo-, sulfate (1:1) (salt)(2068-78-2)