Oxibendazole 奥苯达唑
CAS 20559-55-1 MFCD00133728
化学结构图
SMILES: COC(=O)NC1NC2C=CC(=CC=2N=1)OCCC
化学属性
| Mol. Formula | C12H15N3O3 |
|---|---|
| Mol. Weight | 249.27 |
| Melting Point | 230-231 ºC |
别名和识别编码
| Chemical Name | Oxibendazole |
|---|---|
| CAS Number | 20559-55-1 |
| Synonym | (5-Propoxy-1H-benzimidazol-2-yl)carbamic Acid Methyl Ester (5-丙氧基-1H-苯并咪唑-2-基)氨基甲酸甲酯 Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate 2-Benzimidazolecarbamic acid, 5-propoxy-, methyl ester 5-Propoxy-2-benzimidazolecarbamic acid methyl ester Anthelcide EQ Equitac Loditac Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate Methyl 5-n-propoxy-2-benzimidazole carbamate N-(2-(5-Propoxybenzimidazolyl)) methyl carbamate N-(Propoxy-5, benzimidazolyl)-2, carbamate de methyle OBDZ Oxibendazole SKF 30310 SKF-30310 |
| MDL Number | MFCD00133728 |
| EC Number | 243-877-7 |
| PubChem Substance ID | 354335320 |
| Chemical Name Translation | 奥苯达唑 |
| Wiswesser Line Notation | T56 BM DNJ CMVO1 GO3 |
| Reaxys-RN | 666885 |
| Merck Number | 6936 |
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分类
- Pharmaceuticals
- {SNA} Benzimidazoles, Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks
- {SNA} Analytical Standards, Analytical/Chromatography, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, Life Sciences Standards, Neat Compounds, Pharmacology Standards
- {SNA} Additional Standards, Analytical Standards, Antibiotics Standards, Chromatography, Drugs & Metabolites, Forensic and Veterinary Standards, Life Sciences Standards, Neat Compounds, Pharmaceuticals, Illicit Drugs & Alcohol, Pharmacology Standards, 分析/色谱
- Intermediates & Fine Chemicals,
产品应用
- Anthelmintic.
相关文献及参考
- KarunaKaron, C.S., et al.: J. Parasitol., 66, 929 (1980),
安全信息
GHS Symbol
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 32 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AJVRAH American Journal of Veterinary Research. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940- Volume(issue)/page/year: 38,809,1977
TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Human Cells - not otherwise specified DOSE/DURATION : 2 mg/L REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 31,505,1976
TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Human Leukocyte DOSE/DURATION : 1 mg/L REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 31,505,1976
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 300 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Eff
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - domestic DOSE : 90 mg/kg SEX/DURATION : female 14-21 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - live birth index (measured after birth) REFERENCE : RMVEAG Recueil de Medecine Veterinaire. (Masson Pub. USA, Inc., Year Book Medical Pub., 35 E. Wacker Dr., Chicago IL 60601) V.1- 1824- Volume(issue)/page/year: 152,467,1976
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 100 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : AJVRAH American Journal of Veterinary Research. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940- Volume(issue)/page/year: 38,809,1977
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 30 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : AJVRAH American Journal of Veterinary Research. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940- Volume(issue)/page/year: 38,809,1977
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