CAS 1981-58-4 MFCD00068333-Sulfamethazine Sodium Salt 磺胺二甲基嘧啶钠盐 TAO{mole}

Sulfamethazine Sodium Salt 磺胺二甲基嘧啶钠盐

CAS 1981-58-4 MFCD00068333

化学结构图

SMILES: Cc1cc(C)nc([N-]S(=O)(=O)c2ccc(N)cc2)n1.[Na+]

化学属性

Mol. Formula	C12H13N4NaO2S
Mol. Weight	300
Density	1.392
Stability	对光和热敏感

别名和识别编码

Chemical Name	Sulfamethazine Sodium Salt
MDL Number	MFCD00068333
CAS Number	1981-58-4
Synonym	Sulfamethazine sodium salt 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide 2-(对氨基苯磺酰胺基)-4,6-二甲嘧啶钠磺胺二甲基嘧啶钠盐 Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, monosodium 磺胺二甲嘧啶钠 2-(对氨基苯磺酰胺基)-4,6-二甲嘧啶钠盐磺胺二甲嘧啶钠盐 2-(对氨基苯磺酰胺基)-4,6-二甲嘧啶钠;N-(4,6-二甲基-2-嘧啶基)-4-氨基苯磺酰胺钠盐 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide sodium salt
PubChem Substance ID	87560231
EC Number	217-840-0
Chemical Name Translation	磺胺二甲基嘧啶钠盐
Reaxys-RN	6761844
Merck Number	8915
Wiswesser Line Notation	T6NJ CNJ BMR D2SZW &-NA-
InChI	InChI=1S/C12H13N4O2S.Na/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11;/h3-7H,13H2,1-2H3;/q-1;+1

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产品应用

磺胺类药，用于脑膜炎、肺炎球菌、溶血性链球菌及某些革兰氏阴性杆菌所引起的感染。

安全信息

WGK Germany3

GHS Symbol

Signal word Warning

Hazard statements

H302 Harmful if swallowed 吞食有害

Hazard Codes Xn

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R22 Harmful if swallowed 吞咽有害

RTECSWO9300000

Storage condition 0-10 0-10°C 2-8℃ 储存温度2-8℃

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P301+P312+P330
P501 Dispose of contents/container to..… 处理内容物/容器.....

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1165 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 52,1789,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 605 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 52,1789,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 699 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MIMEAO Minerva Medica.  (Edizioni Minerva Medica, Casella Postale 491,
   I-10126 Turin, Italy) V.1-    1909-  Volume(issue)/page/year: 52,1789,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 974 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,17,1944

其他信息

无臭或几乎无臭，味苦涩，有吸湿性，该品在水中易溶，在乙醇中略溶。