Tegaserod Maleate 马来酸替加色罗
CAS 189188-57-6 MFCD89188576
化学结构图
SMILES: CCCCCNC(=N)N/N=C/C1=CNC2C=CC(=CC1=2)OC.OC(=O)/C=C\C(O)=O
化学属性
| Mol. Weight | 417.46 |
|---|---|
| Mol. Formula | C20H27N5O5 |
别名和识别编码
| CAS Number | 189188-57-6 |
|---|---|
| Chemical Name | Tegaserod Maleate |
| Synonym | 2-[(5-Methoxy-1H-indol-3-yl)methylene]-N-pentylhydrazinecarboximidamide (2Z)-2-Butenedioate HTF 919 SDZ-HTF 919 Tegaserod Hydrogen Maleate Tegibs 6 Zelmac Zelnorm |
| Chemical Name Translation | 马来酸替加色罗 |
信息真实价格透明
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Amines
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- Tegaserod is a gastroproeinetic used in the treatment of irritable bowel syndrome. A selective serotonin 5HT4-receptor partial agonist.
相关文献及参考
- [2]. T C Seerden, et al. Experimental pancreatitis disturbs gastrointestinal and colonic motility in mice: effect of the prokinetic agent tegaserod. Neurogastroenterol Motil. 2007 Oct;19(10):856-64.
- [3]. M D Crowell, et al. The effects of tegaserod, a 5-HT receptor agonist, on gastric emptying in a murine model of diabetes mellitus. Neurogastroenterol Motil. 2005 Oct;17(5):738-43.
- [4]. H-C Pan, et al. Tegaserod, a small compound mimetic of polysialic acid, promotes functional recovery after spinal cord injury in mice. Neuroscience. 2014 Sep 26;277:356-66.
- [5]. D T Beattie, et al. The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo. Br J Pharmacol. 2004 Nov;143(5):549-60.
- Appel, S., et al.: Clin. Pharmacol. Ther., 62, 546 (1997),
- [1]. A E Vickers, et al. In vitro metabolism of tegaserod in human liver and intestine: assessment of drug interactions. Drug Metab Dispos. 2001 Oct;29(10):1269-
