1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one 1,3-二氢-3-[(2,4,6-三甲氧基苯基)亚甲基]-2H-吲哚-2-酮

CAS 186611-52-9 MFCD00118156

化学结构图

186611-52-9
SMILES: COC1C=C(C=C(OC)C=1/C=C1/C(=O)NC2C=CC=CC=2/1)OC

化学属性

Mol. FormulaC18H17NO4
Mol. Weight311.34
Melting Point212.0 to 216.0 deg-C

别名和识别编码

Chemical Name1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one
Synonym 1,3-Dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one SU5607
MDL NumberMFCD00118156
PubChem Substance ID24278111
CAS Number186611-52-9
Reaxys-RN14433656
Chemical Name Translation1,3-二氢-3-[(2,4,6-三甲氧基苯基)亚甲基]-2H-吲哚-2-酮
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分类

  • {SA} A to C, Bioactive Small Molecules, Biochemicals and Reagents, Casein Kinase (CK), Casein kinase 1, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,
  • {SNA} A to C, Bioactive Small Molecule Alphabetical Index, Casein Kinase (CK), Casein kinase 1, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, I, Kinase/Phosphatase Biology, Protein Kinase Inhibitors, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物

相关文献及参考

  • Mashhoon, N., et al, Crystal structure of a conformation-selective casein kinase-1 inhibitor. J. Biol. Chem. 275 , 20052-20060 , (2000) 摘要
  • Behrend, L., et al, IC261, a specific inhibitor of the protein kinase 1 delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects. Oncogene 19 , 5303-5313 , (2000) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition 0-10°C

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. A to C - Enzyme Inhibitors by Enzyme
  7. Casein kinase 1 - A to C
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Kinase Inhibitors - Serine/Threonine Kinase Biology
  7. Casein Kinase (CK) - Serine/Threonine Kinase Inhibitors

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