PD 150606

CAS 179528-45-1 MFCD00949076

化学结构图

179528-45-1
SMILES: OC(=O)/C(/S)=C/C1C=CC(I)=CC=1

化学属性

Mol. FormulaC9H7IO2S
Mol. Weight306.12

别名和识别编码

Chemical NamePD 150606
Synonym (2Z)-3-(4-iodophenyl)-2-mercapto-2-Propenoic acid 3-(4-iodophenyl)-2-mercapto-(Z)-2-propenoic acid PD 150606
MDL NumberMFCD00949076
Chemical Name Translation
PubChem Substance ID329798817
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Calpain and Proteasome Inhibitors, Endoplasmic Reticulum Stress, P-PH, Proteasome Inhibitors, 一氧化氮和细胞应激, 生物活性小分子, 细胞信号转导和神经科学, 细胞内蛋白降解, 细胞生物学
  • {SNA} Bioactive Small Molecules, Calpain and Proteasome Inhibitors, Cell Biology, Cell Signaling and Neuroscience, Endoplasmic Reticulum Stress, Intracellular Protein Degradation, Nitric Oxide and Cell Stress, P, Proteasome Inhibitors

相关文献及参考

  • [2]. 2. Squier MK , et al. Calpain and calpastatin regulate neutrophil apoptosis. J Cell Physiol. 1999 Mar;178(3):311-9.
  • [1]. 1. Wang KK et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92.
  • [1]. 1. Wang KK et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6687-92.
  • [2]. 2. Squier MK , et al. Calpain and calpastatin regulate neutrophil apoptosis. J Cell Physiol. 1999 Mar;178(3):311-9.

安全信息

GHS Symbol
Precautionary statements
  • P301+P310
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H318 Causes serious eye damage 严重伤害眼睛
  • H301 Toxic if swallowed 吞食有毒
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Danger
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Hazard Codes T
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性

系列性分类


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