Tonabersat
CAS 175013-84-0 MFCD75013840
化学结构图
SMILES: CC(=O)C1=CC2[C@H](NC(=O)C3C=C(Cl)C(F)=CC=3)[C@H](O)C(C)(C)OC=2C=C1
化学属性
| Mol. Weight | 391.82 |
|---|---|
| Mol. Formula | C20H19ClFNO4 |
别名和识别编码
| CAS Number | 175013-84-0 |
|---|---|
| Chemical Name | Tonabersat |
| Synonym | N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3- |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Aromatics
- Heterocycles
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- It is a cholinesterase inhibitor for treating and preventing migraine. An antimigraine agent
相关文献及参考
- [2]. Chen Q, et al. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. Nature. 2016 May 18;533(7604):493-8.
- [3]. Kim Y, et al. Tonabersat Prevents Inflammatory Damage in the Central Nervous System by Blocking Connexin43 Hemichannels. Neurotherapeutics. 2017 May 30.
- Saito, R., et al.: Brain Res., 699, 109
- [1]. Silberstein SD, et al. Tonabersat, a gap-junction modulator: efficacy and safety in two randomized, placebo-controlled, dose-ranging studies of acute migraine. Cephalalgia. 2009 Nov;29 Suppl 2:17-27.
- [1]. Silberstein SD, et al. Tonabersat, a gap-junction modulator: efficacy and safety in two randomized, placebo-controlled, dose-ranging studies of acute migraine. Cephalalgia. 2009 Nov;29 Suppl 2:17-27.
- [2]. Chen Q, et al. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. Nature. 2016 May 18;533(7604):493-8.
- [3]. Kim Y, et al. Tonabersat Prevents Inflammatory Damage i
