L-Sepiapterin 墨蝶呤
CAS 17094-01-8 MFCD00210214
化学结构图
SMILES: C[C@H](O)C(=O)C1CNC2NC(N)=NC(=O)C=2N=1
化学属性
| Mol. Formula | C9H11N5O3 |
|---|---|
| Mol. Weight | 237 |
别名和识别编码
| Chemical Name | Sepiapterin |
|---|---|
| Synonym | 墨蝶呤 S-(-)-2-氨基-7,8-二氢-6-(2-羟基-1-氧代丙基)-4(1H)-蝶啶酮 L-Sepiapterin L-Sepiapterin S-(-)-2-氨基-7,8-二氢-6-(2-羟基-1-氧代丙基)-4(1H)-蝶啶酮 |
| MDL Number | MFCD00210214 |
| PubChem Substance ID | 57654606 |
| CAS Number | 17094-01-8 |
| Chemical Name Translation | 墨蝶呤 |
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分类
- {SNA} Asymmetric Synthesis, Bioactive Small Molecules, Cell Biology, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Others, S
- {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Others
- Asymmetric Synthesis, Bioactive Small Molecules, Cell Biology, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Others, S
- {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Other Heterocyclic Building Blocks
相关文献及参考
- [2]. Cho YR, et al. Sepiapterin inhibits cell proliferation and migration of ovarian cancer cells via down-regulation of p70S6K-dependent VEGFR-2 expression. Oncol Rep. 2011;26(4):861‐867.
- Gross et al., Tetrahydrobiopterin synthesisAn absolute requirement for cytokine-induced nitric oxide generation by vascular smooth muscle. J. Biol. Chem. 267 , 25722, (1992) 摘要
- Lelchuk, et al., Constitutive and inducible nitric oxide synthases in human megakaryoblastic cells. J. Pharmacol. Exp. Ther. 262 , 1220-1224, (1992) 摘要
- Schoedon, et al., Regulation of the L -arginine-dependent and tetrahydrobiopterin-dependent biosynthesis of nitric oxide in murine macrophages. Eur. J. Biochem. 213 , 833-834, (1993) 摘要
- [1]. Pannirselvam M
- [1]. Pannirselvam M, et al. Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice. Br J Pharmacol. 2003;140(4):701‐706.
