CHPG
CAS 170846-74-9 MFCD01321059
化学结构图
SMILES: NC(C1C=C(O)C=CC=1Cl)C(O)=O
化学属性
| Mol. Formula | C8H8ClNO3 |
|---|---|
| Mol. Weight | 201.61 |
别名和识别编码
| Chemical Name | CHPG |
|---|---|
| Synonym | α-amino-2-chloro-5-hydroxybenzeneacetic acid (RS)-2-chloro-5-hydroxyphenylglycine α-amino-2-chloro-5-hydroxybenzeneacetic acid CHPG α-amino-2-chloro-5-hydroxybenzeneacetic acid (RS)-2-chloro-5-hydroxyphenylglycine α-amino-2-chloro-5-hydroxybenzeneacetic acid |
| MDL Number | MFCD01321059 |
| PubChem Substance ID | 329775148 |
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专业采购外包团队在线服务
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分类
- {SNA} Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission, Neurotransmitter Receptors
- {SNA} Bioactive Small Molecule Alphabetical Index, C-CH, Neuroscience, Neurotransmission, Neurotransmitter Receptors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- [2]. Chen T, et al. The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway. Int J Mol Med. 2012 Apr;29(4):630-6.
- [1]. Qiu JL, et al. The selective mGluR5 agonist CHPG attenuates SO 2 -induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. Neurochem Int. 2015 Jun-Jul;85-86:46-52.
- [1]. Qiu JL, et al. The selective mGluR5 agonist CHPG attenuates SO 2 -induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. Neurochem Int. 2015 Jun-Jul;85-86:46-52.
- [2]. Chen T, et al. The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway. Int J Mol Med. 2012 Apr;29(4):630-6.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
