• 原料直供
• 试剂商城
• 直接询价

分类

• Inhibitors
• {SNA} ATRP, ATRP Ligands, Apoptosis and Cell Cycle, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DNA Synthesis Inhibitors, DNA metabolism, Materials Science, Polymer Science, Reagents for Controlled Radical Polymerization, Reagents for Polymerization, T
• Heterocycles
• {SNA} ATRP, ATRP Ligands, Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, DNA Synthesis Inhibitors, DNA metabolism, Polymer Science, Reagents for Controlled Radical Polymerization, Reagents for Polymerization, T, 材料科学,
• Chelating Agents & Ligands
• {SNA} ATRP,
• Apop

产品应用

• Membrane-permeable zinc chelator; decreased the intracellular level of zinc and induced apoptosis.

相关文献及参考

• [2]. Rahal ON, et al. Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon cancer cells. Cancer Biol Ther. 2016 Nov;17(11):1139-1148.
• [3]. E Aizenman, et al. Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release. J Neurochem. 2000 Nov;75(5):1878-88.
• Chang, H.-R., et al.: J. Am. Chem. Soc., 112, 6814 (1990),
• Kolenko, V.M.: Apoptosis, 6, 419 (2001),
• Treves, S., et al.: Exp. Cell Res., 21, 339 (1994),
• [1]. Ohkubo M, et al. Heavy metal chelator TPEN attenuates fura-2 fluorescence changes induced by cadmium, mercury and methylmercury. J Vet Med Sci. 2016 Jun 1;78(5):761-7.
• [1]. Ohkubo M, et al. Heavy metal chelator TPEN attenuates fura-2 fluorescence changes induced by cadmium, mercury and methylmercury. J Vet Med Sci. 2016 Jun 1;78(5):761-7.
• [2]. Rahal ON, et al. Chk1 and DNA-PK mediate TPEN-induced DNA damage in a ROS dependent manner in human colon

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