OMAPATRILAT (4S,7S,10aS)-4-((S)-2-巯基-3-苯基丙酰氨基)-5-氧代八氢-2H-吡啶并[2,1-B][1,3]硫杂氮杂-7-甲酸
CAS 167305-00-2 MFCD00935634
化学结构图
SMILES: OC(=O)[C@@H]1CCC[C@@H]2SCC[C@H](NC(=O)[C@@H](S)CC3C=CC=CC=3)C(=O)N12
化学属性
| Mol. Formula | C19H24N2O4S2 |
|---|---|
| Mol. Weight | 408.541 |
别名和识别编码
| Chemical Name | OMAPATRILAT |
|---|---|
| Chemical Name Translation | (4S,7S,10aS)-4-((S)-2-巯基-3-苯基丙酰氨基)-5-氧代八氢-2H-吡啶并[2,1-B][1,3]硫杂氮杂-7-甲酸 |
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相关文献及参考
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- [3]. Ichiki T, et al. Endothelial permeability in vitro and in vivo: protective actions of ANP and omapatrilat in experimental atherosclerosis. Peptides. 2013 Oct;48:21-6.
- [4]. Burrell LM, et al. Antihypertensive and antihypertrophic effects of omapatrilat in SHR. Am J Hypertens. 2000 Oct;13(10):1110-6.
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- [1]. Fryer RM, et al. Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy ofenzymes associated with bradykinin-mediated angioedema.Br J Pharmacol. 2008 Mar;153(5):947-55.
- [2
