DOXEPIN
CAS 1668-19-5 MFCD00599467
化学结构图
SMILES: CN(C)CC/C=C1/C2C=CC=CC=2COC2C=CC=CC=2/1
化学属性
| Mol. Formula | C19H21NO |
|---|---|
| Mol. Weight | 279.41 |
别名和识别编码
| Chemical Name | Dibenz(b,e)oxepin-delta(sup11(6H)),gamma-propylamine, N,N-dimethyl- |
|---|---|
| Wiswesser Line Notation | T C676 BY IO JHJ BU3N1&1 |
| Synonym | 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz(b,e)oxipin Doxepin P 3693A |
| CAS Number | 1668-19-5 |
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安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 147 mg/kg TOXIC EFFECTS : Autonomic Nervous System - parasympatholytic Behavioral - somnolence (general depressed activity) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,863,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 79 mg/kg TOXIC EFFECTS : Autonomic Nervous System - parasympatholytic Behavioral - somnolence (general depressed activity) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,863,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percen
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 26 mg/kg TOXIC EFFECTS : Autonomic Nervous System - parasympatholytic Behavioral - somnolence (general depressed activity) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,863,1965
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 11 mg/kg TOXIC EFFECTS : Autonomic Nervous System - parasympatholytic Behavioral - somnolence (general depressed activity) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Ver
