L-Stepholidine 左旋千金藤啶碱
CAS 16562-13-3 MFCD16562133
化学结构图
SMILES: COC1=C2CN3CCC4C=C(OC)C(O)=CC=4[C@@H]3CC2=CC=C1O |&1:17|
化学属性
| Mol. Weight | 327.41 |
|---|---|
| Mol. Formula | C19H21NO4 |
别名和识别编码
| CAS Number | 16562-13-3 |
|---|---|
| Chemical Name | L-Stepholidine |
| Synonym | (13aS)- 左旋千金藤啶碱 6H-Dibenzo(a,g)quinolizine-2,10-diol, |
| Chemical Name Translation | 左旋千金藤啶碱 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- Aromatics
- Chiral Reagents
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
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相关文献及参考
- [2]. Zhou M, et al. The Neuroprotective Effect of L-Stepholidine on Methamphetamine-Induced Memory Deficits in Mice. Neurotox Res. 2019 Aug;36(2):376-386.
- [3]. Wang W, et al. The effect of L-stepholidine, a novel extract of Chinese herb, on the acquisition, expression, maintenance, and re-acquisition of morphine conditioned place preference in rats. Neuropharmacology. 2007 Feb;52(2):355-61. Epub 2006 Oct 5.
- Smith, B., et al.: Pharm. Res., 17, 1278
- [1]. Ma B, et al. L-stepholidine, a natural dopamine receptor D1 agonist and D2 antagonist, inhibits heroin-induced reinstatement. Neurosci Lett. 2014 Jan 24;559:67-71.
- [1]. Ma B, et al. L-stepholidine, a natural dopamine receptor D1 agonist and D2 antagonist, inhibits heroin-induced reinstatement. Neurosci Lett. 2014 Jan 24;559:67-71.
- [2]. Zhou M, et al. The Neuroprotective Effect of L-Stepholidine on Methamphetamine-Induced Memory Deficits in Mice. Neurotox Res. 2019 Aug;36(2):376-386.
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安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 928 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression REFERENCE : CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 6,156,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 358 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 7,522,1986
