2-(furan-2-yl)-7-phenethyl-6,7-dihydro-5H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-imine 2-(呋喃-2-基)-7-苯乙基-7H-吡唑并[4,3-e][1,2,4]三唑并[1,5-c]嘧啶-5-胺
CAS 160098-96-4 MFCD00933778
化学结构图
SMILES: NC1=NC2=C(C=NN2CCC2C=CC=CC=2)C2=NC(=NN21)C1=CC=CO1
化学属性
| Mol. Formula | C18H15N7O |
|---|---|
| Mol. Weight | 345.36 |
别名和识别编码
| Chemical Name | 2-(furan-2-yl)-7-phenethyl-6,7-dihydro-5H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-imine |
|---|---|
| Synonym | 7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine SCH 58261 |
| MDL Number | MFCD00933778 |
| PubChem Substance ID | 329824547 |
| Chemical Name Translation | 2-(呋喃-2-基)-7-苯乙基-7H-吡唑并[4,3-e][1,2,4]三唑并[1,5-c]嘧啶-5-胺 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Adenosines/P2 Nucleotide Receptor - Antagonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Antagonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience,
- {SNA} Adenosines/P2 Nucleotide Receptor - Antagonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Antagonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives, S
- {SNA
相关文献及参考
- [2]. Varani K, et al. Pharmacological and biochemical characterization of purified A2a adenosine receptors in human platelet membranes by [3H]-CGS 21680 binding. Br J Pharmacol. 1996 Apr;117(8):1693-701.
- [3]. Xi J, et al. Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts. J Mol Cell Cardiol. 2009 Nov;47(5):684-90.
- [4]. Kuzumaki N, et al. Multiple analyses of G-protein coupled receptor (GPCR) expression in the development of gefitinib-resistance in transforming non-small-cell lung cancer. PLoS One. 2012;7(10):e44368.
- [5]. Mediavilla-Varela M, et al. Antagonism of adenosine A2A receptor expressed by lung adenocarcinoma tumor cells and cancer associated fibroblasts inhibits their growth. Cancer Biol Ther. 2013 Sep;14(9):860-8.
- [6]. Wardas J, et al. SCH 58261, a selective adenosine A2A receptor antagonist, decreases the haloperidol-enhanced proenkephalin mRNA expression i
