CAS 15574-96-6 MFCD00864192-4-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-Methylpiperidine 4-(9,10-二氢-4H-苯并[4,5]环庚并[1,2-b]噻吩-4-亚基)-1-甲基哌啶 TAO{mole}

4-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-Methylpiperidine 4-(9,10-二氢-4H-苯并[4,5]环庚并[1,2-b]噻吩-4-亚基)-1-甲基哌啶

CAS 15574-96-6 MFCD00864192

化学结构图

SMILES: CN1CCC(CC1)=C1C2C=CC=CC=2CCC2SC=CC=21

化学属性

Mol. Formula	C19H21NS
Mol. Weight	295.44

别名和识别编码

Chemical Name	4-(9,10-Dihydro-4H-Benzo[4,5]Cyclohepta[1,2-B]Thiophen-4-Ylidene)-1-Methylpiperidine
CAS Number	15574-96-6
Synonym	4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine BC 105 Litec Pizotifen Pizotifen Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine Pizotyline Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine Sandomigram Sandomigran; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine Sandomygran
EC Number	239-632-9
MDL Number	MFCD00864192
Wiswesser Line Notation	T C576 BY FS&T&J BU- DT6N DYTJ A1
Beilstein Registry Number	0753534
PubChem Substance ID	354333208
Chemical Name Translation	4-(9,10-二氢-4H-苯并[4,5]环庚并[1,2-b]噻吩-4-亚基)-1-甲基哌啶
Reaxys-RN	753534
Merck Number	7515

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

分类

{SNA} Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Diversification Ready Pharma-Developed Compounds, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Novartis, PI-PZ, Serotonergics, Serotonergics - Antagonists, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
Sulfur & Selenium Compounds
{SNA} Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,

产品应用

Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant.

安全信息

GHS Symbol

WGK Germany3

Precautionary statements

P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P501 Dispose of contents/container to..… 处理内容物/容器.....
P405 Store locked up. 上锁保管。
P301+P312+P330
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P201 Obtain special instructions before use. 使用前获取专门指示。
P308+P313

Hazard statements

H302 Harmful if swallowed 吞食有害
H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害

RTECSTM7165000

Signal word Warning

Safety Statements

S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Hazard Codes Xn

Risk Statements

R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
R22 Harmful if swallowed 吞咽有害

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 12857 ug/kg/12D-I
TOXIC EFFECTS :
   Liver - jaundice, other or unclassified
REFERENCE :
   AIMDAP Archives of Internal Medicine.  (AMA, 535 N. Dearborn St., Chicago,
   IL 60610)  V.1-    1908-  Volume(issue)/page/year: 144,815,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHMCAA Pharmacologist.  (American Soc. for Pharmacology and Experimental
   Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014)  V.1-    1959-
   Volume(issue)/page/year: 12,297,1970