Bimatoprost 比马前列素
CAS 155206-00-1 MFCD03411999
化学结构图
SMILES: CCNC(=O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2C=CC=CC=2)[C@H](O)C[C@@H]1O
化学属性
| Mol. Formula | C25H37NO4 |
|---|---|
| Mol. Weight | 415.57 |
别名和识别编码
| Chemical Name | Bimatoprost |
|---|---|
| CAS Number | 155206-00-1 |
| Synonym | (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide 17-Phenyl-tri-norprostaglandin F2α-ethyl amide AGN-192024 Bimatoprost Lumigan Prostamide |
| MDL Number | MFCD03411999 |
| Chemical Name Translation | 比马前列素 |
| PubChem Substance ID | 329820253 |
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分类
- Pharmaceuticals
- {SNA} Arachidonic Acid Cascade, Cell Biology, Cell Signaling and Neuroscience, Lipids in Cell Signaling, Prostaglandins
- Chiral Reagents
- {SNA} Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Lipids in Cell Signaling, P-PH, Prostaglandins, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Intermediates & Fine Chemicals,
产品应用
- Bimatoprost is an antiglaucoma agent. Bimatoprost is an synthetic prostamide; structurally related to prostaglandin F2?.
相关文献及参考
- [2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.
- Brandt, J.D., et al.: Ophthalmology, 108, 1023 (2001),
- Quinones, R., et al.: J. Ocul. Pharmacol. Ther., 20, 115 (2004),
- Woodward, D.F., et al.: J. Pharmacol. Exp. Ther., 305, 772 (2003),
- [1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7.
- [1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7.
- [2]. Filippopoulos T, et al. Periorbital changes associated with topical bimatoprost. Ophthal Plast Reconstr Surg. 2008 Jul-Aug;24(4):302-7.
