Arachidonyl Trifluoromethyl Ketone
CAS 149301-79-1 MFCD00236427
化学结构图
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)C(F)(F)F
化学属性
| Mol. Formula | C21H31F3O |
|---|---|
| Mol. Weight | 356.47 |
别名和识别编码
| Chemical Name | Arachidonyl trifluoromethyl ketone |
|---|---|
| Synonym | 1,1,1-Trifluoromethyl-6,9,12,15-heieicosatetraen-2-one AACOCF3 Arach-CF3 Arachidonyl trifluoromethyl ketone |
| MDL Number | MFCD00236427 |
| PubChem Substance ID | 24890647 |
| CAS Number | 149301-79-1 |
| Chemical Name Translation |
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分类
- {SNA} AN-AZ, Bioactive Small Molecule Alphabetical Index, Cannabinoids, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Neurobiology, Neuroscience, P to Q, Pharmacologicals, Phospholipase A2, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
- {SNA} AN-AZ, Bioactive Small Molecules, Biochemicals and Reagents, Cannabinoids, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Neurobiology, Neuroscience,
相关文献及参考
- [2]. Schanstra JP, et al. Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. JCI Insight. 2019;4(10):e125638. Published 2019 May 16.
- [3]. Loweth AC, et al. A specific inhibitor of cytosolic phospholipase A2 activity, AACOCF3, inhibits glucose-induced insulin secretion from isolated rat islets. Biochem Biophys Res Commun. 1996;218(2):423-427.
- [1]. Riendeau D, et al. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J Biol Chem. 1994;269(22):15619-15624.
- [1]. Riendeau D, et al. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. J Biol Chem. 1994;269(22):15619-15624.
- [2]. Schanstra JP, et al. Systems biology identifies cy
