L-161,982
CAS 147776-06-5 MFCD09959710
化学结构图
SMILES: CC1C=CSC=1C(=O)NS(=O)(=O)C1=CC=CC=C1C1C=CC(CN2C(CCCC)=NN(C3=CC=CC=C3C(F)(F)F)C2=O)=CC=1
化学属性
| Mol. Formula | C32H29F3N4O4S2 |
|---|---|
| Mol. Weight | 654.731 |
别名和识别编码
| Chemical Name | L-161,982 |
|---|---|
| Chemical Name Translation |
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相关文献及参考
- [2]. Cherukuri DP, et al. The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.Exp Cell Res. 2007 Aug 15;313(14):2969-79.
- [3]. Chen L, et al. L161982 alleviates collagen-induced arthritis in mice by increasing Treg cells and down-regulating Interleukin-17 and monocyte-chemoattractant protein-1 levels.BMC Musculoskelet Disord. 2017 Nov 16;18(1):462.
- [1]. Li X, et al.The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.J Oral Pathol Med. 2017 Nov;46(10):991-997.
- [1]. Li X, et al.The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.J Oral Pathol Med. 2017 Nov;46(10):991-997.
- [2]. Cherukuri DP, et al. The EP4 receptor antagonist, L-161,982, bloc
