3-Aminopyridine-2-Carboxylic Acid 3-氨基吡啶-2-羧酸

CAS 1462-86-8 MFCD00090153

化学结构图

1462-86-8
SMILES: Nc1cccnc1C(=O)O

化学属性

Mol. FormulaC6H6N2O2
Mol. Weight138.12
Melting Point218-220°C
Density1.422
Boiling Point386.6°C at 760 mmHg

别名和识别编码

Chemical Name3-Aminopyridine-2-Carboxylic Acid
CAS Number1462-86-8
Alfabeta NameAMINOPYRIDINECARBOXYLICACID 32---
MDL NumberMFCD00090153
Synonym 3-Aminopicolinic Acid {LY} 3-Aminopicolinic Acid {} {LY} 3-Aminopicolinic Acid {} {} {LY} 3-Aminopicolinic Acid {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3-Aminopicolinic Acid {} {} {} {} {} {} {} {} {} {} {}
EC Number215-971-8
Beilstein Registry Number0003600
Chemical Name Translation3-氨基吡啶-2-羧酸
InChIKeyBOOMHTFCWOJWFO-UHFFFAOYSA-N
LabNetwork Molecule IDLN00008746
PubChem Substance ID73836
InChIInChI=1S/C6H6N2O2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,7H2,(H,9,10)
Canonical SMILESO=C(O)C1=NC=CC=C1N
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分类

  • Heterocycles
  • Aromatics
  • Amines
  • {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines

相关文献及参考

  • Stukenbrock, H., et al.: J. Med. Chem., 51, 2196 (2008),
  • Dominguez, C., et al.: Bioorg. Med. Chem. Lett., 17, 6003 (2007),

安全信息

Warnings IRRITANT
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P333+P313
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P501a
Hazard Codes Xi
RTECSUS5175000
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Endocrine - hypoglycemia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 17,1065,1974

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H319 Causes serious eye irritation 严重刺激眼睛

其他信息

  • 下游产品:
  • 上游原料:氢氧化钠 --> 盐酸 --> 硫酸 --> 溴 --> 乙酐 --> 高锰酸钾 --> 三氟乙酸 --> 无水醋酸钠 --> 乙酰胺 --> 喹啉酸 --> 6-氯-2-甲基-3-硝基吡啶 --> 锌汞齐
  • Hazard Note:Irritant
  • 存储注意事项:氮气保护
  • 检测方法:HPLC,NMR
  • MOL 文件:1462-86-8.mol

系列性分类


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