Rizatriptan benzoate 2-(5-((1H-1,2,4-三唑-1-基)甲基)-1H-吲哚-3-基)-N,N-二甲基乙胺苯甲酸盐
CAS 145202-66-0 MFCD00866224
化学结构图
SMILES: CN(C)CCC1=CNC2C=CC(CN3C=NC=N3)=CC=21.OC(=O)C1C=CC=CC=1
化学属性
| Mol. Formula | C15H19N5·C7H6O2 |
|---|---|
| Mol. Weight | 391 |
| Melting Point | 178.0 to 182.0 deg-C |
别名和识别编码
| Chemical Name | Rizatriptan benzoate |
|---|---|
| CAS Number | 145202-66-0 |
| Synonym | MK-0462 MK-462 MK-462 Benzoate |
| MDL Number | MFCD00866224 |
| Chemical Name Translation | 2-(5-((1H-1,2,4-三唑-1-基)甲基)-1H-吲哚-3-基)-N,N-二甲基乙胺苯甲酸盐 |
| PubChem Substance ID | 354334261 |
| Reaxys-RN | 7066526 |
| Merck Number | 8241 |
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分类
- {SNA} Agonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, R, Serotonergics, Serotonergics - Agonists, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
- Heterocycles
- Neurochemicals
- Pharmaceuticals
- {SNA} Agonists, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience,
产品应用
- A selective serotonin 5-HTID receptor agonist. Structurally derived from tryptamine.
相关文献及参考
- Cheng, H., et al.: Biopharm. Drug Dispos., 17, 17 (1996),
- [1]. Sciberras DG, et al. Initial human experience with MK-462 (rizatriptan): a novel 5-HT1D agonist. Br J Clin Pharmacol. 1997 Jan;43(1):49-54.
安全信息
GHS Symbol
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P308+P313
- H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
- H303 May be harmfully swallowed 吞食可能有害
- R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
