3-((2’-(1H-Tetrazol-5-Yl)-[1,1’-Biphenyl]-4-Yl)Methyl)-2-Butyl-1,3-Diazaspiro[4.4]Non-1-En-4-One 3-((2’(1H-四唑-5-基)-[1,1’-联苯]-4-基)甲基)-2-丁基-1,3-二氮杂螺[4.4]壬-1-烯-4-酮
CAS 138402-11-6 MFCD00864464
化学结构图
SMILES: CCCCC1=NC2(CCCC2)C(=O)N1CC1C=CC(=CC=1)C1=CC=CC=C1C1NN=NN=1
化学属性
| Mol. Formula | C25H28N6O |
|---|---|
| Mol. Weight | 429 |
| Melting Point | 180-181 |
别名和识别编码
| Chemical Name | 3-((2’-(1H-Tetrazol-5-Yl)-[1,1’-Biphenyl]-4-Yl)Methyl)-2-Butyl-1,3-Diazaspiro[4.4]Non-1-En-4-One |
|---|---|
| CAS Number | 138402-11-6 |
| Alfabeta Name | TETRAZOLYLBIPHENYLYLMETHYLBUTYLDIAZASPIRONONENONE H32151142134414.[[]]((()))------------------,,'' |
| MDL Number | MFCD00864464 |
| Synonym | 2-Butyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, Avapro, BMS-186295, SR-47436 Irbesartan |
| Chemical Name Translation | 3-((2’(1H-四唑-5-基)-[1,1’-联苯]-4-基)甲基)-2-丁基-1,3-二氮杂螺[4.4]壬-1-烯-4-酮 |
| LabNetwork Molecule ID | LN00173692 |
| Beilstein Registry Number | 6620400 |
| Reaxys-RN | 6620400 |
| PubChem Substance ID | 172088930 |
| Merck Number | 5083 |
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信息真实价格透明
资金保障
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分类
- {SNA} Angiotensin Receptor Antagonists, Angiotensins, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bristol-Myers Squibb, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, I, Membrane Protein Biology Tools, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, Sanofi Aventis, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
- {SNA} Angiotensin Receptor Antagonists, Angiotensins, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Bristol-Myers Squibb,
相关文献及参考
- [2]. Ruiz E, et al. Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis: inhibition by the angiotensin AT1 receptor antagonist irbesartan. Eur J Pharmacol. 2007 Jul 19;567(3):231-9. Epub 2007 Apr 6.
- [1]. Schupp M, et al. Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation. 2004 May 4;109(17):2054-7. Epub 2004 Apr 26.
- [1]. Schupp M, et al. Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation. 2004 May 4;109(17):2054-7. Epub 2004 Apr 26.
- [2]. Ruiz E, et al. Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis: inhibition by the angiotensin AT1 receptor antagonist irbesartan. Eur J Pharmacol. 2007 Jul 19;567(3):231-9. Epub 2007 Apr 6.
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
