(-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane （ - ）-2β-甲酯基-3β-（4 -碘苯基）去甲托烷
CAS 136794-87-1 MFCD07995048
化学结构图
SMILES: COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2)C1C=CC(I)=CC=1
化学属性
| Mol. Formula | C15H18INO2 |
|---|---|
| Mol. Weight | 371.21 |
别名和识别编码
| Chemical Name | (-)-2β-Carbomethoxy-3β-(4-iodophenyl)nortropane |
|---|---|
| CAS Number | 136794-87-1 |
| Synonym | nor-?-CIT (1R,2S,3S,5S)-3-(4-Iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester (-)-2β-甲氧羰基-3β-(4-碘苯基)去甲托烷 |
| MDL Number | MFCD07995048 |
| PubChem Substance ID | 24892422 |
| Chemical Name Translation | （ - ）-2β-甲酯基-3β-（4 -碘苯基）去甲托烷 |
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分类
- Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, C-CH, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Biogenic Amine Transport Inhibitors, C-CH, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission,
产品应用
- An inhibitor of the serotonin (5-HT) transporter.
相关文献及参考
- Bergstrom, K.A., et al.: Eur. J. Nucl. Med., 24, 596 (1997),
- Booij, J., et al.: Eur. J. Nucl. Med., 25, 1666 (1998),
- Reneman, L., et al., Comparative in vivo study of iodine-123-labeled β-CIT and nor-β-CIT binding to serotonin transporters in rat brain. Synapse 34 , 77-80, (1999) 摘要
- Booij, J., et al., Iodine-123 labelled nor-β-CIT binds to the serotonin transporter in vivo as assessed by biodistribution studies in rats. Eur. J. Nucl. Med. 25 , 1666-1669, (1998) 摘要
- Bergstrom, K.A., et al., In vitro and in vivo characterisation of nor-β-CIT: a potential radioligand for visualisation of the serotonin transporter in the brain. Eur. J. Nucl. Med. 24 , 596-601, (1997) 摘要
