7-(Benzyloxy)Quinoline 7-苄氧基喹啉
CAS 131802-60-3 MFCD00870296
化学结构图
SMILES: C(OC1=CC2N=CC=CC=2C=C1)C1C=CC=CC=1
化学属性
| Mol. Formula | C16H13NO |
|---|---|
| Mol. Weight | 235.28 |
别名和识别编码
| Chemical Name | 7-(Benzyloxy)Quinoline |
|---|---|
| MDL Number | MFCD00870296 |
| CAS Number | 131802-60-3 |
| Synonym | 7-Benzyloxyquinoline |
| Chemical Name Translation | 7-苄氧基喹啉 |
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分类
- {SNA} Application Index, B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell
- {SNA} Application Index, Cell Signaling Enzymes, Cytochrome P450, Cytochrome P450 3A4, Detection and Quantitation, Drug and Xenobiotic Metabolism, Enzyme Substrates, Multi-Drug Resistance and Drug Metabolism, Reagents, Substrates by Enzyme, Xenobiotics And Drug Metabolism Substrates, Xenobiotics and Drug Metabolism, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
- Application Index, B, Bioactive Small Molecules,
相关文献及参考
- Stresser, D. M., Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates. Drug Metab. Dispos. 28 , 1440, (2000)
- Lu, P., et al., Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-4-trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4. Drug Metab. Dispos. 29(11) , 1473-1479, (2001) 摘要
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
