CAS 130-26-7 MFCD00006787-Clioquinol 氯碘羟喹 TAO{mole}

Clioquinol 氯碘羟喹

CAS 130-26-7 MFCD00006787

化学结构图

SMILES: Oc1c(I)cc(Cl)c2cccnc12

化学属性

Mol. Formula	C9H5ClINO
Mol. Weight	305.50
Melting Point	171-174°C
TSCA	Yes
Solubility	<0.1 G/100 ML AT 20 ºC
Boiling Point	350.4±37.0 °C at 760 mmHg

别名和识别编码

Chemical Name	Clioquinol
Synonym	Clioquinol {LY} Clioquinol {} {LY} Clioquinol {} {} {LY} Clioquinol {} {} {} {LY} Clioquinol {} {} {} {} {LY} Clioquinol {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clioquinol
MDL Number	MFCD00006787
PubChem Substance ID	87565356
Beilstein Registry Number	21,98
CAS Number	130-26-7
EC Number	204-984-4
Reaxys-RN	153637
Merck Number	5031
Chemical Name Translation	氯碘羟喹
Wiswesser Line Notation	T66 BNJ GG II JQ
LabNetwork Molecule ID	LN00194812
InChI	InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
Canonical SMILES	ClC1=C(C=CC=N2)C2=C(O)C(I)=C1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

WGK Germany3

GHS Symbol

Precautionary statements

P501 Dispose of contents/container to..… 处理内容物/容器.....
P302+P352+P333+P313+P362+P364
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P310
P301+P312+P330
P302+P350
P337+P313
P308+P313
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P201 Obtain special instructions before use. 使用前获取专门指示。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P305+P351+P338+P337+P313
P405 Store locked up. 上锁保管。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。

Hazard statements

H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
H315 Causes skin irritation 会刺激皮肤
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H319 Causes serious eye irritation 严重刺激眼睛
H301 Toxic if swallowed 吞食有毒
H302 Harmful if swallowed 吞食有害

Hazard Codes T

RTECSVC5075000

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Signal word Danger {} {} {} {} {} {} {TCI}

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S24 Avoid contact with skin 避免皮肤接触；
S37 Wear suitable gloves 戴适当手套；
S22 Do not breathe dust 不要吸入粉尘；

Risk Statements

R25 Toxic if swallowed 吞咽有毒
R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
R42/43

UN Number UN 2811 6.1/PG 3 2811

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

Packing GroupIII

Hazard Class6.1(b)

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 23,1566,1973

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 175 mg/kg
TOXIC EFFECTS :
   Liver - other changes
REFERENCE :
   AJTMAQ American Journal of Tropical Medicine.  (Baltimore, MD)  V.1-31,
   1921-51.  For publisher information, see AJTHAB.  Volume(issue)/page/year:
   24,29,1944

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 1400 mg/kg/20D-I
TOXIC EFFEC

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 11 gm/kg/36W
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - optic nerve neuropathy
   Sense Organs and Special Senses (Eye) - visual field changes
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 1,1015,1972

{hazar

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year:

TYPE OF TEST

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 1 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 26,159,1974

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rat Cells - not otherwise specified
DOSE/DURATION           : 10 umol/L
REFERENCE :
   JTSCDR Journal of Toxicological Sciences.  (Japanese Soc. of Toxicological
   Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku,
   Tokyo 113, Japan)  V.1-    1976-  Volume(issue)/page/year: 12,97,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1320 mg/kg
SEX/DURATION            : female 7-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
   Reproductive - Effects on Newborn - physical
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 14,211,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 9000 mg/kg
SEX/DURATION            : female 30 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 14,75,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 528 mg/kg
SEX/DURATION            : female 7-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 14,211,1977

其他信息

用途一:用作抗寄生虫药
Sigma Aldrich:130-26-7(sigmaaldrich)
类别:有毒物质
Alfa Aesar:5-氯-8-羟基-7-碘喹啉,98% 5-Chloro-8-hydroxy-7-iodoquinoline, 98%(130-26-7)
毒性分级:高毒
MOL 文件:130-26-7.mol
Acros Organics:5-chloro-7-iodoquinolin-8-ol(130-26-7)
氯碘羟喹价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 C0187 5-氯-8-羟基-7-碘喹啉 5-Chloro-8-hydroxy-7-iodoquinoline 25G 312元 2014/06/02 C0187 5-氯-8-羟基-7-碘喹啉 5-Chloro-8-hydroxy-7-iodoquinoline 250G 1350元 2010/06/21 SB01341EE 氯碘羟喹 5-chloro-7-iodoquinolin-8-ol 50 GR 405元
可燃性危险特性:可燃; 火场分解有毒氮氧化物, 碘化物和氯化物烟雾
储运特性:库房低温, 通风, 干燥; 与食品原料分开存放
刺激数据:皮肤-人 3%/2周对皮肤有影响
灭火剂:水, 二氧化碳, 干粉, 砂土
MSDS 信息:Chloroiodeoquim(130-26-7).msds
TCI Shanghai:5-氯-8-羟基-7-碘喹啉 5-Chloro-8-hydroxy-7-iodoquinoline,>;98.0%(T)(130-26-7)
急性毒性:口服-大鼠 LD50: >; 5000 毫克/公斤; 口服-小鼠 LD50: 69 毫克/公斤