Prednisone Acetate 醋酸泼尼松

CAS 125-10-0 MFCD00200229

化学结构图

125-10-0
SMILES: CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(=O)C[C@@]21C

化学属性

Mol. FormulaC23H28O6
Mol. Weight400.51
Appearance 25 白色或类白色结晶性粉末，无臭，味苦。不溶于水，微溶于乙醇、丙酮和乙酸乙酯，易溶于氯仿(1：6)。比旋光度[α] +186°(二噁烷)；无水乙醇溶液在238nm波长处有最大吸收。 D

别名和识别编码

Chemical NamePrednisone Acetate
CAS Number125-10-0
Synonym ######## nisone 4-diene-3,11,20-trione,17,21-dihydroxy-pregna-21-acetate Cortancyl Nisone delta-corlin 17Α,21-二羟基-Δ1,4-孕甾二烯-3,11,20-三酮-21-醋酸酯,17Α,21-DIHYDROXY-1,4-PREGNADIENE-3,11,20-TRIONE-21-ACETATE PREDNISONE ACETATE [2-[(8s,9s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate Prednisone 21-acetate Delta-corlin 去氢可的松醋酸酯 delta'-Dehydrocortisone acetate Ferrosan [2-[(8S,9S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate Delcortin 1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione-21-acetate 醋酸脱氢可的松 17α,21-Dihydroxypregna-1,4-diene-3,11,20-trioneacetate Pregna-1,4-diene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy- 醋酸去氢皮质素 deltalone 17 ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE-21-ACETATE ACETIC ACID 2-((8S,9S,10R,13S,14S,17R)-17-HYDROXY-10,13-DIMETHYL-3,11-DIOXO-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-3H-CYCLOPENTA[A]PHENA 1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE delcortin 乙酸脱氢可的松 prednisone 21-acetate 11,20-trione,21-(acetyloxy)-17-hydroxy-pregna-4-diene-3 醋酸泼尼松 Prednisone acetate 17a,21-二羟基孕甾-1,4-二烯-3,11,20-三酮 21-醋酸酯 delta’-dehydrocortisoneacetate Dehydrocortisone acetate 乙酸去氢可的松 1,4-Pregnadien-17-alpha,21-diol-3,11,20-trione-21-acetate 乙酸强的松 {Chemicalbook}
EC Number204-726-0
MDL NumberMFCD00200229
Chemical Name Translation醋酸泼尼松
Wiswesser Line NotationL E5 B666 CV OV AHTTT&J A1 E1 FV1OV1 FQ
Beilstein Registry Number2342061
LabNetwork Molecule IDLN00859473
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • Adrenocortical steroid antiinflammatory.

相关文献及参考

  • Ma, Y., J. Steroid Biochem. Mol. Biol., 117, 146 (2009),
  • Zhang, L., et al.: App. Biochem. Biotechnol., 159, 642 (2009),
  • [1]. Prednisolone acetate

安全信息

RTECSTU4154085 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 330 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   56,23,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 135 mg/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   56,23,1980

其他信息

  • 用途一:生化研究，肾上腺皮质激素类药物，具有抗炎、抗过敏等作用。
  • MOL 文件:125-10-0.mol
  • 上游原料:二氧化硒 --> 醋酸可的松
  • 方法一:醋酸可的松经二氧化硒脱氢而得。

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Glucocorticoid Receptor  (糖皮质激素受体)

相关产品推荐