CAS 1227-61-8 MFCD00079457-Mefexamide Hydrochloride 美非沙胺盐酸盐 TAO{mole}

Mefexamide Hydrochloride 美非沙胺盐酸盐

CAS 1227-61-8 MFCD00079457

化学结构图

SMILES: CCN(CC)CCNC(=O)COc1ccc(OC)cc1

化学属性

Mol. Formula	C15H24N2O3
Mol. Weight	280.41

别名和识别编码

Chemical Name	Mefexamide Hydrochloride
MDL Number	MFCD00079457
CAS Number	1227-61-8
Synonym	ANP 297 Mefexamide 美非沙胺盐酸盐 MP 297 U-25701A 对-甲氧基苯氧基乙酸 2-(二乙胺基)乙酰胺 N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide Mefaxadyne 2-(p-Methoxyphenoxy)-N-(2-(diethylamino)ethyl)acetamide Acetamide, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)- NP 297 Timodyne Mephexamide Mexephenamide
PubChem Substance ID	4045
EC Number	214-963-1
Chemical Name Translation	美非沙胺盐酸盐
Wiswesser Line Notation	2N2&2MV1OR DO1
Beilstein Registry Number	2219009
InChI	InChI=1S/C15H24N2O3/c1-4-17(5-2)11-10-16-15(18)12-20-14-8-6-13(19-3)7-9-14/h6-9H,4-5,10-12H2,1-3H3,(H,16,18)

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安全信息

RTECSAB7175000

GHS Symbol

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P302+P350
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。

Hazard statements

H330 Fatal if inhaled 吸入致命
H310 Fatal in contact with skin 皮肤接触致命
H300 Fatal if swallowed 吞食致命

WGK Germany3

Signal word Danger

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S22 Do not breathe dust 不要吸入粉尘；

Hazard Codes T+

Risk Statements

R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMXXAJ French Medicament Patent Document.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Discontinued.
   Volume(issue)/page/year: #2702M

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMPYAT Annales Medico-Psychologiques.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-Series 11, V.2, 1843-1921; V.80-    1922-
   Volume(issue)/page/year: 123,141,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 1,444,1966