CAS 12122-67-7 MFCD00067266-Zinc Ethylene-1, 2-Bisdithiocarbamate 代森锌 TAO{mole}

Zinc Ethylene-1, 2-Bisdithiocarbamate 代森锌

CAS 12122-67-7 MFCD00067266

化学结构图

SMILES: [Zn+2].[S-]C(=S)NCCNC([S-])=S

化学属性

Mol. Formula	C4H6N2S4Zn
Mol. Weight	276

别名和识别编码

Chemical Name	Zinc Ethylene-1, 2-Bisdithiocarbamate
Synonym	Blightox Micide Novozir N Perosin 75B Tiezene Asporum Perozine Tiazin ENT 14,874 Novozin N 50 Kupratsin Zineb 75 Daisen Dithane Z-78 Novozir Zebenide Cynkotox Zineb 80 CHEM zineb Zineb Lirotan Sperlox-Z Perozin Dithane 65 Discon-Z Phytox Tritoftorol Cineb Perosin 1,2-Ethanediylbis(carbamodithioato) (2-)-S,S'-zinc Thiodow Novozir N 50 Tsineb Tanazon 亚乙基双(二硫代氨基甲酸)锌 Bercema Polyram Z Zink-(N,N'-aethylen-bis(dithiocarbamat)) Zinosan Parzate C Novosir N 代森锌 Carbadine Ditiamina Blizene Zinc ethylenebisdithiocarbamate Aaphytora Zebtox Zidan Zinc ethylene-1,2-bisdithiocarbamate Ethylenebis(dithiocarbamic acid), zinc salt Dithane Z Kypzin Pamosol 2 forte Devizeb Aspor ((1,2-Ethanediylbis(carbamodithioato))(2-))zinc Crittox Ethylenebis(dithiocarbamato)zinc Hexathane Parzate zineb Lonacol Zineb 75 WP 1,2-Ethanediylbiscarbamodithioic acid, zinc complex Dipher
MDL Number	MFCD00067266
PubChem Substance ID	24869277
Beilstein Registry Number	4165797
EC Number	235-180-1
Chemical Name Translation	代森锌
Wiswesser Line Notation	T9MYS-ZN-SYMTJ BUS FUS
CAS Number	12122-67-7

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安全信息

RTECSZH3325000

GHS Symbol

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

Hazard statements

H317 May cause an allergic skin reaction 可能导致皮肤过敏
H335 May cause respiratory irritation 可能导致呼吸道刺激

WGK Germany3

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Safety Statements

S46 If swallowed, seek medical advice immediately and show this container or label 食入时，立即求医并出示容器/标签；
S8 Keep container dry 保持容器干燥；
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Hazard Codes Xi

Risk Statements

R37 Irritating to respiratory system 刺激呼吸道
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
   Liver - tumors
REFERENCE :
   VPITAR Voprosy Pitaniya.  Problems of Nutrition.  (V/O Mezhdunarodnaya
   Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11-    1952-
   Volume(issue)/page/year: 29,71,1970

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2600 mg/kg/13W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   VRDEA5 Vrachebnoe Delo.  Medical Practice.  (V/O Mezhdunarodnaya Kniga,
   113095 Moscow, USSR) No.1-    1918-  Volume(issue)/page/year: (9),100,1966

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 53580 mg/kg/94W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Gastrointestinal - colon tumors
REFERENCE :
   VPITAR Voprosy Pitaniya.  Problems of Nutrition.  (V/O Mezhdunarodnaya
   Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11-    1952-
   Volume(issue)/page/year: 29,71,1970

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 273 gm/kg/2.5Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Endocrine - thyroid tumors
   Skin and Appendages - tumors
REFERENCE :
   JTSCDR Journal of Toxicological Sciences.  (Japanese Soc. of Toxicological
   Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bun

{hazard_c

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
   Behavioral - ataxia
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 4,93,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 4450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,121,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1940 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
   GKNT, 1982  Volume(issue)/page/year: -,121,1982

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
   eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
   A420,1984

TYPE

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 50 ppm/4D (Continuous)
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 206,25,1988

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(1),80,1980

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   ARTODN Archives of Toxicolo

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 10 ug/kg
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 17(3),32,1973

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 1000 ppm
REFERENCE :
   MMAPAP Mycopathologia et Mycologia Applicata.  (The Hague, Netherlands)
   V.5-54(4), 1950-74.  For publisher information, see MYCPAH.
   Volume(issue)/page/year: 50,233,1973

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 1 nmol/plate
REFERENCE :
   MSERDS Microbiology Series.  (Marcel Dekker, 270 Madison Ave., New York, NY
   10

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4 gm/kg
SEX/DURATION            : female 11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 11,239,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 8 gm/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   EKMMA8 Eksperimentalna Meditsina i Morfologiya.  (Hemus, Blvd. Russki 6,
   Sofia, Bulgaria) V.1-    1962-  Volume(issue)/page/year: 10,226,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4 gm/kg
SEX/DURATION            : female 13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
   EKMMA8 Eksperimentalna Meditsina i Morfologiya.  (Hemus, Blvd. Russki 6,
   Sofia, Bulgaria) V.1-    1962-  Volume(issue)/page/year: 10,226,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 28 gm/kg
SEX/DURATION            : female 6-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - feto