BRL 44408
CAS 118343-19-4 MFCD02262218
化学结构图
SMILES: CC1C2=CC=CC=C2CN1CC1NCCN=1.OC(=O)/C=C\C(O)=O
化学属性
| Mol. Formula | C17H21N3O4 |
|---|---|
| Mol. Weight | 331.37 |
别名和识别编码
| Chemical Name | BRL 44408 maleate salt |
|---|---|
| CAS Number | 118343-19-4 (free base) |
| Synonym | 2-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-2,3-dihydro-1-methyl-1H-isoindole 2-[2H-(1-Methyl-1,3-dihydroisoindole)methyl]-4,5-dihydroimidazole maleate salt |
| MDL Number | MFCD02262218 |
| PubChem Substance ID | 329773239 |
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分类
- Adrenergics, Adrenergics - Antagonists, Analytical Standards, Analytical/Chromatography, Antagonists, Approved Therapeutics/Drug Candidates, B, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, GlaxoSmithKline, Membrane Protein Biology Tools, Neat Compounds, Neuroscience, Neurotransmission, Neurotransmitters,
- {SNA} Adrenergics,
产品应用
- Selective ?2A-adrenoceptor antagonist . Increases hippocampal noradrenaline release following systemic administration.
相关文献及参考
- Young, et al.: Eur. J. Pharmacol., 168, 381 (1989),
- Kiss, et al.: Brain Res., 238, 674 (1995),
- Callado, et al.: Eur. J. Pharmacol., 35, 366 (1999),
- Willems, et al. Br. J. Pharmacol. 132 , 1292-1298, (2001) 摘要
