Lafutidine 拉呋替丁
CAS 118288-08-7 MFCD00867520
化学结构图
SMILES: O=C(CS(=O)CC1=CC=CO1)NC/C=C\COC1=CC(CN2CCCCC2)=CC=N1
化学属性
| Mol. Formula | C22H29N3O4S |
|---|---|
| Mol. Weight | 431.554 |
别名和识别编码
| Chemical Name | Lafutidine |
|---|---|
| Synonym | (Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide |
| Chemical Name Translation | 拉呋替丁 |
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相关文献及参考
- [2]. Tetsuhiro Sugiyama, et al. Lafutidine facilitates calcitonin gene-related peptide (CGRP) nerve-mediated vasodilation via vanilloid-1 receptors in rat mesenteric resistance arteries. J Pharmacol Sci. 2008 Mar;106(3):505-11.
- [3]. Mitsuaki Okayama, et al. Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on dextran sulfate sodium-induced colonic inflammation through capsaicin-sensitive afferent neurons in rats. Dig Dis Sci. 2004 Oct;49(10):1696-704.
- [1]. Motoko Nakano, et al. Possible involvement of host defense mechanism in the suppression of rat acute reflux esophagitis by the particular histamine H2 receptor antagonist lafutidine. Pharmacology. 2012;90(3-4):205-11.
- [1]. Motoko Nakano, et al. Possible involvement of host defense mechanism in the suppression of rat acute reflux esophagitis by the particular histamine H2 receptor antagonist lafutidine. Pharmacology. 2012;90(3-4):205-11.
- [2]. Tetsuhiro Sugiyama, et al
安全信息
GHS Symbol
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
