Luzindole Luzindole.
CAS 117946-91-5 MFCD00672498
化学结构图
SMILES: CC(=O)NCCC1C2C=CC=CC=2NC=1CC1C=CC=CC=1
化学属性
| Mol. Formula | C19H20N2O |
|---|---|
| Mol. Weight | 292.38 |
| TSCA | No |
| Melting Point | 104.0 to 108.0 deg-C |
别名和识别编码
| Chemical Name | Luzindole |
|---|---|
| CAS Number | 117946-91-5 |
| Synonym | 2-Benzyl-N-acetyltryptamine Luzindole N-Acetyl-2-benzyltryptamine N-Acetyl-2-benzyltryptamine N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide |
| MDL Number | MFCD00672498 |
| PubChem Substance ID | 354335145 |
| Chemical Name Translation | Luzindole. |
| Reaxys-RN | 8156010 |
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分类
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, L, Melatonin - Receptor Antagonists, Melatonins, Membrane Protein Biology Tools,
- {SNA} Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, L, Melatonin - Receptor Antagonists, Melatonins, Membrane Protein Biology Tools, Neurobiology, Neuroscience, Pharmacologicals, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学,
产品应用
- A melatonin receptor antagonist.
相关文献及参考
- [2]. Constantinescu CS, et al. Luzindole, a melatonin receptor antagonist, suppresses experimental autoimmune encephalomyelitis. Pathobiology. 1997;65(4):190-4.
- [3]. Dubocovich ML Antidepressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in the mouse behavioral despair test. Eur J Pharmacol. 1990 Jul 3;182(2):313-25.
- Dubocovitch, M.L.: J. Pharmacol. Exp. Ther., 233, 902 (1988)
- [1]. Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch
- [1]. Dubocovich ML, et al. Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol. 1997 Mar;355(3):365-75.
