Fumonisin B2 伏马菌素B2, 来源于串珠镰刀菌
CAS 116355-84-1 MFCD00133350
化学结构图
SMILES: CCCC(C)CC(OC(=O)CC(CC(O)=O)C(O)=O)C(CC(C)CCCCCCC(O)CC(O)C(C)N)OC(=O)CC(CC(O)=O)C(O)=O
化学属性
| Mol. Formula | C34H59NO14 |
|---|---|
| Mol. Weight | 705.83 |
别名和识别编码
| Chemical Name | Fumonisin B2 from Fusarium moniliforme |
|---|---|
| CAS Number | 116355-84-1 |
| Synonym | (2R,2'R)-1,2,3-Propanetricarboxylic Acid 1,1'-[(1S,2R)-1-[(2S,9R,11S,12S)-12-Amino-4,9,11-trihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] Ester Fumonisin B2 |
| MDL Number | MFCD00133350 |
| PubChem Substance ID | 24894857 |
| Chemical Name Translation | 伏马菌素B2, 来源于串珠镰刀菌 |
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SA} Biochemicals and Reagents, Core Bioreagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, R to Z, Research Essentials, Sphingosine acyltransferase
- Chiral Reagents
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Amines
- {SNA} Core Bioreagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, R to Z, Research Essentials, Sphingosine acyltransferase, 生化试剂, 酶、抑制剂和底物
产品应用
- A mycotoxin produced by mold associated with corn. Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.
相关文献及参考
- [2]. Shephard GS, et al. Disruption of sphingolipid metabolism in non-human primates consuming diets of fumonisin-containing Fusarium moniliforme culture material. Toxicon. 1996 May;34(5):527-34.
- [3]. Wei T, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013;6(4):270-4.
- 1. Marasas, W.F., et al., Fumonisins disrupt sphingolipid metabolism, folate transport, and neural tube development in embryo culture and in vivo: a potential risk factor for human neural tube defects among populations consuming fumonisin-contaminated maize J. Nutr. 134 , 711-716, (2004)
- 2. Morgensen, J.M., et al., Production of Fumonisin B 2 and B 4 by Aspergillus niger on grapes and raisins J. Agric. Food Chem. 58 , 954-958, (2010) 摘要
- Klosowski, G., et al.: Biores. Technol., 101, 9723 (2010),
- Merrill, A.H., and Wang, E., Enzymes of ceramide biosynthesis Meth. Enzymol. 209 , 427-437, (1992
安全信息
GHS Symbol
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P301+P310
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P302+P350
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H330 Fatal if inhaled 吸入致命
- H310 Fatal in contact with skin 皮肤接触致命
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H351 Suspected of causing cancer 怀疑致癌
- H300 Fatal if swallowed 吞食致命
- H319 Causes serious eye irritation 严重刺激眼睛
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S22 Do not breathe dust 不要吸入粉尘；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
