N-Ethyl-3-Hydroxy-N,N-Dimethylbenzenaminium Chloride N-乙基-3-羟基-N,N-二甲基苯胺氯化物
CAS 116-38-1 MFCD00055064
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SNA} A to C, Acetylcholinesterase, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cholinesterase, acetyl, E, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Valeant
产品应用
- A reversible Acetylcholinesterase inhibitor.
相关文献及参考
- Lyon, R., et al.: J. Pharm. Sci., 95, 1549 (2006),
- Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009),
- Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 10,327,1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 52 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,121,1958
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 8500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,185,1955
其他信息
- MOL 文件:116-38-1.mol
- Sigma Aldrich:116-38-1(sigmaaldrich)