trans-Retinal 全-反式-视黄醛

CAS 116-31-4 MFCD00001550

化学结构图

116-31-4
SMILES: CC(C=CC=C(C)C=CC1=C(C)CCCC1(C)C)=CC=O

化学属性

Mol. FormulaC20H28O
Mol. Weight284
Appearance 有16种立体异构体。13种已被化学合成，其中11-顺式异构体为天然视蛋白（opsins）中的发色物质。全E型：结晶。熔点64-65℃。7E，9Z，11E，13E型：熔点56-58℃。
Melting Point62-64

别名和识别编码

Chemical Nametrans-Retinal
CAS Number116-31-4
Synonym 11 cis Retinal 11-cis-Retinal Aldehyde, Vitamin A Axerophthal E-Retinal Retinal Retinaldehyde Retinene Retinin Vitamin A Aldehyde Vitamin A1 aldehyde Vitamin-A-aldehyde all trans-Retinal all-trans-Retinal alpha-Retinene {} {} {} {} {uni_hamburg} 视黄醇/维生素A
MDL NumberMFCD00001550
PubChem Substance ID638015
EC Number204-135-8
Chemical Name Translation全-反式-视黄醛
Beilstein Registry Number1914183
LabNetwork Molecule IDLN01311111
InChIInChI=1S/C20H28O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,15H,7,10,14H2,1-5H3/b9-6+,12-11+,16-8+,17-13+
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信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Aldehydes,
  • Retinoids,
  • {SNA} Aldehy
  • {uni_hamburg} no charge; carbocycle; alicycle; 6RingOnly; 6ring; aldehyde; 1fragment
  • {SNA} Aldehydes, Building Blocks, C13-C60, Carbonyl Compounds, Chemical Synthesis, Cofactor, Gene Regulation, Isoprenoid, Organic Building Blocks, Vitamin A, Vitamins, 代谢组学, 代谢通路, 代谢通路图中的代谢产物和辅酶分子, 抗肿瘤药物, 生化试剂, 癌症研究, 细胞生物学
  • {SNA} Aldehydes, Antitumor Agents, Building Blocks, C13-C60, Cancer Research, Carbonyl Compounds,
  • {SNA} Aldehydes, Building Blocks, C

产品应用

  • Corotenoid component of the visual pigments. All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase.

相关文献及参考

  • Ball, et al.: Biochem. J., 42, 516 (1948),
  • O?Brien, D.F., et al.: Science, 218, 961 (1982),
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15
  • Short: II/3 Title: Luminescence of Organic Substances Author: Schmillen, A.; Legler, R. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/3 Year: 1967 ISBN: 3-540-03895-7 ISBN: 978-3-540-03895-5 Internet Resource: DOI:10.1007/b86158 RefComment: 270 figs., VIII, 416 pages. Hardcover Abstract: For more than 1000 luminescent organic substances the most important data are represented as wave numbers of absorption and emission bands, decay times and quantum efficiencies. Additional tables contain further information for restricted groups

安全信息

GHS Symbol
RTECSVH6407000
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H315 Causes skin irritation 会刺激皮肤
  • H332 Harmful if inhaled 吸入有害
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R38 Irritating to skin 刺激皮肤
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 100 umol/L
REFERENCE :
   ONCOBS Oncology.  (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 
     1967-  Volume(issue)/page/year: 44,356,1987

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rat Mammary gland
DOSE/DURATION           : 3 umol/L
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 70,949,1983

Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P312
  • P302+P352
  • P304+P312
  • P304+P340
  • P308+P313
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类

  1. Life Science 生命科学
  2. Cancer Research
  3. Antitumor Agents - Cancer Research
  4. Gene Regulation - Antitumor Agents
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Aldehydes - Carbonyl Compounds
  6. C13-C60 - Aldehydes
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Vitamins
  4. Folic Acid
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Biochemicals Found in Plants
  4. Carbohydrates
  5. Simple sugars
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Metabolomics
  4. Metabolic Pathways
  5. Metabolites and Cofactors on the Metabolic Pathways Chart
  6. Cholesterol
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Nutrition Research
  4. Biochemicals Found in Plants
  5. Carbohydrates
  6. Simple sugars
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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