Zileuton 齐留通
CAS 111406-87-2 MFCD00866097
化学结构图
SMILES: CC(C1=CC2=CC=CC=C2S1)N(O)C(N)=O
化学属性
| Mol. Formula | C11H12N2O2S |
|---|---|
| Mol. Weight | 236 |
别名和识别编码
| Chemical Name | Zileuton |
|---|---|
| Synonym | Zileuton (±)-N-hydroxy-N-(1-benzo[b]thien-2-ylethyl)urea |
| MDL Number | MFCD00866097 |
| Chemical Name Translation | 齐留通 |
| LabNetwork Molecule ID | LN00010201 |
| CAS Number | 111406-87-2 |
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专业采购外包团队在线服务
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分类
- {SNA} Abbott, Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Lipids in Cell Signaling, Lipoxygenase
- {SNA} Abbott, Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Lipids in Cell Signaling, Lipoxygenase, Z, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- [2]. Kuvibidila S, et al. Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease. Ochsner
- [3]. Gounaris E, et al. Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation. PLoS One. 2015 Mar 6;10(3):e0121402
- [4]. Lei C, et al. Zafirlukast attenuates advanced glycation end-products (AGEs)-induced degradation of articular extracellular matrix (ECM). Int Immunopharmacol. 2019;68:68-73.
- [1]. Abueid L, et al. Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. Anatol J Cardiol. 2016 Nov 10
- [1]. Abueid L, et al. Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. Anatol J Cardiol. 2016 Nov 10
- [2]. Kuvibidila S, et al. Hydroxyurea and
安全信息
GHS Symbol
- P305+P351+P338
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36 Irritating to eyes 刺激眼睛
- R22 Harmful if swallowed 吞咽有害
