CAS 11089-65-9 MFCD00065709-Tunicamycin 衣霉素 TAO{mole}

Tunicamycin 衣霉素

CAS 11089-65-9 MFCD00065709

化学结构图

SMILES: CC(=O)N[C@@H]1[C@@H](O[C@@H](CO)[C@H](O)[C@H]1O)O[C@@H]1O[C@H](C[C@@H](O)[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@H](O)[C@H]1NC(=O)/C=C/CCCCCCCCC(C)C

化学属性

Mol. Formula	(CH2)nC29H44N4O16
Mol. Weight	817
TSCA	No

别名和识别编码

Chemical Name	Tunicamycin
Beilstein Registry Number	6888090
PubChem Substance ID	24900473
MDL Number	MFCD00065709
Synonym	Tunicamycin from Streptomyces sp. 来源于链霉菌属
CAS Number	11089-65-9
Merck Number	14,9819
Chemical Name Translation	衣霉素

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分类

{SA} AIDS and Viral Research Reagents, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antibiotics by Application, Antifungal, Antineoplastic and Immunosuppressive Antibiotics, Antiviral, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Chemical Activators and Inhibitors of ER Stress, Chemical Structure Class, Endoplasmic Reticulum Stress, Glycobiology, Immune Cell Signaling and Blood, Immune System Regulation, Inhibitors, Inhibitors and Substrates, Interferes with Protein Synthesis, L - Z, Mechanism of Action, Nucleosides,
{SNA} Anti

安全信息

RTECSYO7980200

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

GHS Symbol

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P301+P310

Hazard statements

H300 Fatal if swallowed 吞食致命

WGK Germany3

Signal word Danger

Hazard Codes 6.1 T+

Safety Statements

S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Risk Statements

R26/28 Very toxic by inhalation and if swallowed 吸入及吞食都有剧毒
R28 Very toxic if swallowed 吞咽极毒
R33 Danger of cumulative effects 有累积作用的危险

Packing GroupII

UN Number 3462 UN3462

Storage condition Moisture & Light Sensitive

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 4 ug/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 39,1148,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 ug/kg
SEX/DURATION            : female 6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 28,13A,1983