PF-998425
CAS 1076225-27-8 MFCD17215970
化学结构图
SMILES: [C-]#[N+]C1C=CC(=CC=1C(F)(F)F)[C@@H]1CCCC[C@@H]1O |&1:12,17|
化学属性
| Mol. Weight | 269.26 |
|---|---|
| Mol. Formula | C14H14F3NO |
别名和识别编码
| Synonym | 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile |
|---|---|
| MDL Number | MFCD17215970 |
| CAS Number | 1076225-27-8 |
| Chemical Name | PF-998425 |
| PubChem Substance ID | 329823718 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Androgen, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Cytokines, Growth Factors and Hormones, Fluorination Ready Pharma-Developed Compounds, Hormones, P-PH, Pfizer Compounds, Steroid Hormones, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Androgen, Approved Therapeutics/Drug Candidates, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Pfizer Compounds, Steroid Hormones
相关文献及参考
- Li, J.J., et al., Rational design and synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J. Med. Chem. Oct 16th ed.,, (2008)
安全信息
GHS Symbol
- P305+P351+P338
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- R36 Irritating to eyes 刺激眼睛
- R22 Harmful if swallowed 吞咽有害
