Loxiglumide 4-(3,4-二氯苯甲酰胺基)-5-((3-甲氧基丙基)(戊基)氨基)-5-氧代戊酸
CAS 107097-80-3 MFCD00866772
化学结构图
SMILES: CCCCCN(CCCOC)C(=O)C(CCC(O)=O)NC(=O)C1C=C(Cl)C(Cl)=CC=1
化学属性
| Mol. Formula | C21H30Cl2N2O5 |
|---|---|
| Mol. Weight | 461.38 |
别名和识别编码
| Chemical Name | Loxiglumide |
|---|---|
| Synonym | (+-)-4-((3,4-Dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)-5-oxopentanoic acid 4-[(3,4-dichlorobenzoyl)amino]-5-[(3-methoxypropyl)pentylamino]-5-oxo-pentanoic acid CR 1505 CR 1505 D,L-4-(3,4-Dichlorobenzoylamino)-5-(N-3-methoxypropylpentylamino)-5-oxo-pentanoic acid Loxiglumide |
| MDL Number | MFCD00866772 |
| CAS Number | 107097-80-3 |
| PubChem Substance ID | 329825180 |
| Chemical Name Translation | 4-(3,4-二氯苯甲酰胺基)-5-((3-甲氧基丙基)(戊基)氨基)-5-氧代戊酸 |
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分类
- {SNA} Antagonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cholinergics, L, Neuroscience, Neurotransmission, Neurotransmitters
- {SNA} Antagonists, Bioactive Small Molecule Alphabetical Index, Cholinergics, L, Neuroscience, Neurotransmission, Neurotransmitters, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
相关文献及参考
- [1]. Jia D, et al. Effect of endogenous cholecystokinin on the course of acute pancreatitis in rats. World J Gastroenterol. 2015 Jul 7;21(25):7742-53.
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 396 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4769389
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JSONAU Journal of Surgical Oncology. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1969- Volume(issue)/page/year: 53,47,1993
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 460 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JSONAU Journal of Surgical Oncology. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1969- Volume(issue)/page/year: 53,47,1993
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JSONAU Journal of Surgical Oncology. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1969- Volume(issue)/page/year: 53,47,1993
