(R)-1-Methyl-3-pyrrolidinol (R)-(-)-1-甲基-3-羟基吡咯烷

CAS 104641-60-3 MFCD03788747

化学结构图

104641-60-3
SMILES: CN1C[C@@H](O)CC1 |&1:3|

化学属性

Mol. FormulaC5H11NO
Mol. Weight101
Refractive index1.4630 to 1.4670
Boiling Point50-52
Density0.921
Flash Point71°C(lit.)
TSCANo

别名和识别编码

Chemical Name(R)-1-Methyl-3-pyrrolidinol
CAS Number104641-60-3
Alfabeta NameHYDROXYMETHYLPYRROLIDINE R31()----
MDL NumberMFCD03788747
Synonym (R)-(-)-3-羟基-N-甲基吡咯烷 (3R)-1-Methylpyrrolidin-3-ol (R)-(-)-1-Methyl-3-pyrrolidinol (3R)-1-Methylpyrrolidin-3-ol (R)-(-)-3-羟基-N-甲基吡咯烷 (R)-N-Methyl-3-pyrrolidinol (R)-(-)-1-甲基-3-吡咯烷醇 (R)-N-Methyl-3-pyrrolidinol
PubChem Substance ID87560086
EC Number000-000-0
Beilstein Registry Number4349393
Chemical Name Translation(R)-(-)-1-甲基-3-羟基吡咯烷
Reaxys-RN4349393
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Pyrrolidines
  • {SA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Pyrrolidines

相关文献及参考

  • 1. Isakovic, L.; et al., Constrained (-)-S-adenosyl-L-homocysteine (SAH) analogues as DNA methyltransferase inhibitors Bioorg. Med. Chem. Lett. 19 , 2742-2746, (2009)
  • 2. Moorjani, M.; et al., 2,6-Diaryl-4-acylaminopyrimidines as potent and selective adenosine A2A antagonists with improved solubility and metabolic stability Bioorg. Med. Chem. Lett. 18 , 5402-5405, (2008)
  • 3. Gobbini, M.; et al., Novel Analogues of Istaroxime, a Potent Inhibitor of Na + ,K + -ATPase: Synthesis and Structure-Activity Relationship J. Med. Chem. 51 , 4601-4608, (2008)
  • 4. Wu, W.-M.; et al., Stereoisomers of N-substituted soft anticholinergics and their zwitterionic metabolite based on glycopyrrolate - syntheses and pharmacological evaluations Pharmazie 63 , 200-209, (2008)
  • Product of Toray Industries, Inc.

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H227 Combustible liquid 可燃液体
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P370+P378
  • P305+P351+P338+P337+P313
Signal word
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Storage condition Air Sensitive & Hygroscopic 0-10°C

系列性分类


相关产品推荐