(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-戊烯酸

CAS 10417-94-4 MFCD00065716

化学结构图

10417-94-4
SMILES: CCCCC/C=C/C/C=C/CCCCCCCCCC(O)=O

化学属性

Mol. FormulaC20H30O2
Mol. Weight302.46
Refractive index1.4970 to 1.5010
Density0.943
Melting Point-54- -53
Flash Point93°C(lit.)

别名和识别编码

Chemical Name(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid
CAS Number10417-94-4
Synonym {uni_hamburg} (all-Z)-5,8,11,14,17-Eicosapentaenoic Acid EPA Timnodonic Acid (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid Ropufa 70 (all-Z)-5,8,11,14,17-Eicosapentaenoic acid 5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)- EPA 45G C20H30O2 (cis-5,8,11,14,17-eicosapentaenoic acid) cis-5,8,11,14,17-eicosapentaenoic acid Incromega E 7010SR 顺式-5,8,11,14,17-二十碳五烯酸 Icosapentaenoic Acid Icosapent EPA 二十碳五烯酸 二十碳五烯酸
PubChem Substance ID87569696
Beilstein Registry Number2(2)470
MDL NumberMFCD00065716
Chemical Name Translation(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-戊烯酸
Reaxys-RN1714433
Merck Number3531
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分类

  • Alphabetic, Analytical Standards, Analytical/Chromatography, Applications, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Chromatography, E, EA - EO, FA/FAME/Lipids/Steroids, Fats (fatty acids, FAMEs, glycerides), Edible Oils, Sterols, Fatty Acids, Fatty Acids and conjugates, Fatty Acyls, Food & Beverage Analysis, Food & Beverage Standards, Free Fatty Acids, Functional Foods, Lipid Analytical Standards, Lipids, Neats, Nutrition Research, Omega 3 fatty acids and derivatives, Other Lipid Related Pro

产品应用

  • 本品有与二十二碳六烯酸相似的性质，但不及DHA强。有降低血液粘度，减少血栓，改善血清，降低血糖、保护脑血管、抗过敏及抗癌作用。用作食品添加剂，用于孕妇及婴儿奶粉；也用作医药，治疗动脉硬化及血栓。

相关文献及参考

  • [2]. Huan, M., et al., Suicide attempt and n-3 fatty acid levels in red blood cells: a case control study in China. Biol Psychiatry, 2004. 56(7): p. 490-6.
  • Bergstrom, S., et al.: J. Biol. Chem., 239, PC 4006 (1964),
  • Kremer, J.M., et al.: Ann. Intern. Med., 106, 497 (1987),
  • Merck: 14,3531 Beilstein:2(2)470
  • Short: IV/15A
  • Srivastava, K.C., et al.: Biochem. Exp. Biol., 16, 317 (1980),
  • [1]. Martins, J.G., EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta-analysis of randomized controlled trials. J Am Coll Nutr, 2009. 28(5): p. 525-42.
  • [1]. Martins, J.G., EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: evidence from a meta-analysis of randomized controlled trials. J Am Coll Nutr, 2009. 28(5): p. 525-42.
  • [2]. Huan, M., e

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H227 Combustible liquid 可燃液体
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes C
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P370+P378
  • P403+P235
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word
Safety Statements
Risk Statements
Storage condition <0°C <;0 储存温度-20°C ,干冰运输; 充氩保存 储存温度： -20°C，干冰运输
Packing GroupIII
UN Number

其他信息

  • 天然以其甘油酯的形式存在于海鱼的肉、脂肪中，尤其是深海鱼的眼窝周围脂肪中含量更丰富。本品易氧化，易对光、热、氧敏感，氧化后颜色变深。通常加入维生素E及儿茶酚等抗氧化剂。是一种多烯不饱和脂肪酸。

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Fatty Acyls - Lipids
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. E - Bioactive Small Molecules
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Carboxylic Acids - Carbonyl Compounds
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Carbonyl Compounds 羰基化合物
  5. Carboxylic Acids - Carbonyl Compounds
  6. C13 to C42+ - Carboxylic Acids
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. E - Alphabetic
  5. EA - EO - E
  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Chromatography - Analytical Standards
  4. Food &amp; Beverage Standards - Chromatography
  5. FA/FAME/Lipids/Steroids - Food &amp; Beverage Standards
  6. Free Fatty Acids - FA/FAME/Lipids/Steroids
  7. Neats - Free Fatty Acids
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Fatty Acyls - Lipids
  5. Fatty Acids and conjugates - Fatty Acyls
  6. Unsaturated Fatty Acids and Derivatives - Fatty Acids and conjugates
  7. Polyunsaturated - Unsaturated Fatty Acids and Derivatives
  8. Omega 3 fatty acids and derivatives - Polyunsaturated
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Enzyme - Enzyme Inhibitors
  6. L to O - Enzyme Inhibitors by Enzyme
  7. Lipoxygenase (5-) - L to O
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Heterocyclic Building Blocks - Chiral Building Blocks
  5. Benzofurans - Heterocyclic Building Blocks
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Heterocyclic Building Blocks - Chiral Building Blocks
  5. Benzopyrans - Heterocyclic Building Blocks
  1. Functional Group 官能团索引
  2. carboxylic acid salt
  1. Life Science 生命科学
  2. Biochemistry / Glyco-Chemistry
  3. Higher Fatty Acids & Higher Alcohols
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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