3-((Bis(Diisopropylamino)Phosphino)oxy)Propanenitrile 2-氰乙基-N,N,N’,N’-四异丙基亚磷酰二胺

CAS 102691-36-1 MFCD00012213

化学结构图

102691-36-1
SMILES: CC(C)N(C(C)C)P(OCCC#N)N(C(C)C)C(C)C

化学属性

Mol. FormulaC15H32N3OP
Mol. Weight301.41
Refractive index1.4680 to 1.4720
Boiling Point100
Density0.949
Stability易吸潮
Flash Point60°C(lit.)
Appearance colorless liq.

别名和识别编码

Chemical Name3-((Bis(Diisopropylamino)Phosphino)oxy)Propanenitrile
CAS Number102691-36-1
Synonym 2-Cyanoethoxybis(N,N-diisopropylamino)phosphine 2-氰乙基N,N,N′,N′-四异丙基亚磷酰二胺 Bis(diisopropylamino)(2-cya Bis(diisopropylamino)(2-cyanoethoxy)phosphine N,N,N?,N?-Tetrakis(1-methylethyl)phosphorodiamidous Acid 2-Cyanoethyl Ester 双(二异丙基氨基)(2-氰乙氧基)膦
PubChem Substance ID87560237
Beilstein Registry Number3590103
MDL NumberMFCD00012213
Reaxys-RN3590103
EC Number250-023-7
Chemical Name Translation2-氰乙基-N,N,N’,N’-四异丙基亚磷酰二胺
LabNetwork Molecule IDLN00188898
InChIKeyRKVHNYJPIXOHRW-UHFFFAOYSA-N
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分类

  • {SA} Building Blocks, Chemical Biology, Chemical Synthesis, Coupling Reagents, Nucleoside Chemistry, Organic Building Blocks, Phosphoramidites, Phosphorus Compounds
  • Phosphorylating and Phosphitylating Agents
  • {SNA} Building Blocks, Chemical Synthesis, Organic Building Blocks, Phosphoramidites, Phosphorus

产品应用

  • 用于合成亚磷酰化核苷酸的试剂

相关文献及参考

  • 1. Bioconjug. Chem. 15 , 638-646, (2004) 摘要
  • Bioorg. Med. Chem. 12 , 2843-2851, (2004) 摘要
  • Bioorg. Med. Chem. 12 , 2385-2396, (2004) 摘要
  • Corp MSDS 1 (1), 938:A / FT-IR 2 (1), 1551:B / FT-NMR 1 (1), 1469:C / RegBook 1 (1), 1095:H / Structure Index 1 , 169:A:6

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H261 In contact with water releases flammable gas 与水接触时释放可燃气体。
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 3
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P231+P232
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241+P242+P243
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P302+P352+P332+P313+P362+P364
  • P303+P361+P353
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P342+P311
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P370+P378
  • P403+P235
  • P422 Store contents under… 存储目录在…之下。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger Warning
UN Number 1993
Storage condition 0-10 贮存温度:-20 °C 0-10°C
Safety Statements
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S3 Keep in a cool place 保存在阴凉处;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R42/43
Packing GroupIII
Hazard Class3

系列性分类


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