CAS 10265-92-6 MFCD00041808-Methamidophos TAO{mole}

Methamidophos

CAS 10265-92-6 MFCD00041808

化学结构图

SMILES: COP(N)(=O)SC

化学属性

Mol. Formula	C2H8NO2PS
Mol. Weight	141.14
Melting Point	42-45 °C

别名和识别编码

Chemical Name	Phosphoramidothioic acid, O,S-dimethyl ester
Synonym	Phosphoramidothioic acid, O,S dimethyl ester BAY 71628 SRA 5172 Hamidop Chevron 9006 甲胺磷 O'S-Dimethylthiophosphoramidat O,S-Dimethyl phosphoramidothioate; Phosphoramidothioic acid O,S-dimethyl ester NSC 190987 Acephate-met Thiophosphorsaeure-O,S-dimethylesteramid O,S-Dimethylamidothiophosphorsäureester CKB 1220 Monitor (insecticide) Bayer 5546 Bayer 71628 Filitox Tahmabon O,S dimethyl phosphoramidothioate O,S-Dimethyl phosphoramidothioate RE 9006 O,S-Dimethyl-amidothiophosphat Monitor phosphoramidothioic acid, O,S-dimethyl ester Metamidophos O,S-Dimethylamidothiophosphat Chevron ortho 9006 Pillaron Phosphoramidothioic acid, O,S-dimethyl ester O,S-dimethyl phosphoroamidothioate O,S-Dimethyl thiophosphoramide Ortho 9006 Sniper Methamidophos methamidophos (ISO) ortho 9006 ortho Monitor O,S-Dimethyl ester amide of amidothioate Methyl phosphoramidothioate ((MeO)(MeS)P(O)(NH2)) Metamidofos estrella ENT 27,396 Tamaron
Beilstein Registry Number	1098870
PubChem Substance ID	24860205
MDL Number	MFCD00041808
EC Number	233-606-0
CAS Number	10265-92-6
Wiswesser Line Notation	1SPZS&O1

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安全信息

GHS Symbol

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P305+P351+P338
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P273 Avoid release to the environment. 避免释放到环境中。
P301+P310
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。

Hazard statements

H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
H330 Fatal if inhaled 吸入致命
H311 Toxic in contact with skin 皮肤接触中毒
H300 Fatal if swallowed 吞食致命

WGK Germany3

Signal word Danger

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes T+;N T+,N

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S1/2 None 上锁保管并避免儿童触及；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Risk Statements

R50 Very toxic to aquatic organisms 对水生生物极毒
R24 Toxic in contact with skin 与皮肤接触有毒
R26/28 Very toxic by inhalation and if swallowed 吸入及吞食都有剧毒

RTECSTB4970000

Restrict 剧毒化学品

Warnings 危化品目录(2015) 危险化学品

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 162 mg/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
   eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
   A265,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARSIM* Agricultural Research Service, USDA Information Memorandum.
   (Beltsville, MD 20705)  Volume(issue)/page/year: 20,7,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 18,189,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 5,149,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - domestic
DOSE/DURATIO

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 250 ug/L
REFERENCE :
   ZNCBDA Zeitschrift fuer Naturforschung, Section C: Biosciences.  (Verlag der
   Zeitschrift fuer Naturforschung, Postfach 2645, D-7400 Tuebingen, Fed. Rep.
   Ger.)  V.29-    1974-  Volume(issue)/page/year: 42,21,1987

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 96 mg/kg/2W (Intermittent)
REFERENCE :
   ZNCBDA Zeitschrift fuer Naturforschung, Section C: Biosciences.  (Verlag der
   Zeitschrift fuer Naturforschung, Postfach 2645, D-7400 Tuebingen, Fed. Rep.
   Ger.)  V.29-    1974-  Volume(issue)/page/year: 42,21,1987

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 6 mg/kg
REFERENCE :
   ZNCBDA Zeitschrift fuer Naturforschung, Section C: Biosciences.  (Verlag der
   Zeitschrift fuer Naturforsch

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 2 mg/L
REFERENCE :
   ZNCBDA Zeitschrift fuer Naturforschung, Section C: Biosciences.  (Verlag der
   Zeitschrift fuer Naturforschung, Postfach 2645, D-7400 Tuebingen, Fed. Rep.
   Ger.)  V.29-    1974-  Volume(issue)/page/year: 42,21,1987

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 6 mg/kg
REFERENCE :
   ZNCBDA Zeitschrift fuer Naturforschung, Section C: Biosciences.  (Verlag der
   Zeitschrift fuer Naturforschung, Postfach 2645, D-7400 Tuebingen, Fed. Rep.
   Ger.)  V.29-    1974-  Volume(issue)/page/year: 42,21,1987

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TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 4 mg/kg
SEX/DURATION            : male 5 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   ZYYZEW Zhongguo Yaolixue Yu Dulixue Zazhi.  (Chinese Pharmacological
   Society, 27 Tai-Ping Road, Beijing 100850, China)  V.1-    1986-
   Volume(issue)/page/year: 2,142,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
   VEMJA8 Veterinary Medical Journal.  (Cairo Univ., Faculty of Veterinary
   Medicine, Giza, Egypt) V.1-    1953-  Volume(issue)/page/year: 34,357,1986

Methamidophos

CAS 10265-92-6 MFCD00041808

化学结构图

化学属性

别名和识别编码

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