5-Methyl-N-phenyl-2-1H-pyridone-d5
CAS 1020719-62-3 MFCD120719623
化学结构图
SMILES: CC1=CN(C(=O)C=C1)C1C([*])=C([*])C([*])=C([*])C=1[*] |$;;;;;;;;;;2H;;2H;;2H;;2H;;2H$|
化学属性
| Mol. Weight | 190.25 |
|---|---|
| Mol. Formula | C12H6D5NO |
别名和识别编码
| CAS Number | 1020719-62-3 |
|---|---|
| Chemical Name | 5-Methyl-N-phenyl-2-1H-pyridone-d5 |
| Synonym | Pirfenidone-d5 |
| Chemical Name Translation |
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分类
- Aromatics
- Isotope Labelled Compounds
- Metabolites
产品应用
- A deuterated metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes.
相关文献及参考
- [2]. Nakazato H, et al. A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-alpha at the translational level. Eur J Pharmacol. 2002 Jun 20;446(1-3):177-85.
- [3]. Inomata M, et al. Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis. Respir Res. 2014 Feb 8;15:16.
- [1]. Burghardt I, et al. Pirfenidone inhibits TGF-beta expression in malignant glioma cells. Biochem Biophys Res Commun. 2007 Mar 9;354(2):542-7.
- [1]. Burghardt I, et al. Pirfenidone inhibits TGF-beta expression in malignant glioma cells. Biochem Biophys Res Commun. 2007 Mar 9;354(2):542-7.
- [2]. Nakazato H, et al. A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-alpha at the translational level. Eur J Pharmacol. 2002 Jun 20;446(1-3):177-85.
- [3]. Inomata M, et al. Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis. Respir Res. 2014
