Basic Orange 14 碱性橙 14
CAS 10127-02-3 MFCD00081043
化学结构图
SMILES: Cl.Cl.CN(C)C1=CC2=NC3C=C(C=CC=3C=C2C=C1)N(C)C.CN(C)C1=CC2=NC3C=C(C=CC=3C=C2C=C1)N(C)C.Cl[Zn]Cl
化学属性
| Mol. Formula | C17H19N3·HCl·0.5ZnCl2 |
|---|---|
| Mol. Weight | 370 |
| TSCA | No |
| Melting Point | 165 ºC |
| Solubility | 可溶 |
别名和识别编码
| Chemical Name | Basic Orange 14 |
|---|---|
| Synonym | 3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double saltC.I. 46005 Acridine Orange hemi(zinc chloride) salt Basic Orange 14 |
| Beilstein Registry Number | 3734978 |
| PubChem Substance ID | 87561823 |
| CAS Number | 10127-02-3 |
| EC Number | 233-353-6 |
| MDL Number | MFCD00081043 |
| Reaxys-RN | 10510633 |
| Chemical Name Translation | 碱性橙 14 |
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分类
- {SNA} Apoptosis Detection, Apoptosis and Cell Cycle, Biochemicals, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
- {SA} Apoptosis Detection, Apoptosis and Cell Cycle, Biochemicals, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Core Bioreagents, Fluorescent Probes, Labels, Particles and Stains, Fluorescent Stains, Life Science Reagents for DNA/RNA Electrophoresis, Molecular Biology, Molecular Biology Reagents, Nucleic Acid Electrophoresis, Nucleic Acid Electrophoresis Stains, Nucleic Acid Gel Stains, Reagents, Research Essentials, Stains & Dyes
相关文献及参考
- Bruno, J.G., et al., Highly selective acridine and ethidium staining of bacterial DNA and RNA. Biotech. Histochem. 71 , 130-136, (1996) 摘要
- Durrieu F, et al., Synthesis of Bcl-2 in response to anthracycline treatment may contribute to an apoptosis-resistant phenotype in leukemic cell lines. Cytometry 36 , 140-149, (1999) 摘要
- Beil. 22 ,V,11,326
- Biological stain.
- Baisch H, et al., Degradation of apoptotic cells and fragments in HL-60 suspension cultures after induction of apoptosis by camptothecin and ethanol. Cell Prolif. 32 , 303-319, (1999) 摘要
- Darzynkiewicz, Z., et al., Features of apoptotic cells measured by flow cytometry. Cytometry 13 , 795-808, (1992) 摘要
- Carmichael, G.G. and McMaster, G.K., The analysis of nucleic acids in gels using glyoxal and acridine orange. Meth. Enzymol. 65 , 380-391, (1980) 摘要
安全信息
- H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P308+P313
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
GHS Symbol
